Publications associées à Accident d'exposition au sang

Degradation study on molecules released from laser-based jet injector

Christophe Moser, Barbora Lavickova, Jan Krizek

Development of needle-free methods to administer injectable therapeutics has been researched for a few decades. We focused our attention on a laser-based jet injection technique where the liquid-jet actuation mechanism is based on optical cavitation. This ...

2021

Repetitive regime of highly focused liquid microjets for needle-free injection

Christophe Moser, Paul Delrot, Jan Krizek

Fast liquid jets are investigated for use as a needle-free drug delivery system into an elastic tissue such as skin. Using smaller jet diameters in a repetitive regime can mitigate bruising and pain associated with current injectors. In this study, we aim ...

Nature Research2020

Bistable Puncturing Tool for Retinal Vein Cannulation

Simon Nessim Henein, Yves Bellouard, Charles Baur, Lisa Anaïs Jeanne Bonnefoy

An innovative surgical tool prototype dedicated to safe puncturing has been developed for the treatment of retinal vein occlusions (RVOs). The tool is manufactured monolithically by femtolaser printing in fused silica. It consists of a programmable bistabl ...

2020

Programmable Multistable Mechanisms for Safe Surgical Puncturing

Simon Nessim Henein, Charles Baur, Ilan Vardi, Andrea Lovera, Thomas Jean Julien Fussinger, Mohamed Gamal Abdelrahman Ahmed Zanaty, Arno Rogg, David Lambelet

We present novel medical devices for safe surgical puncturing, in particular a cannula for the treatment of retinal vein occlusion (RVO). This passive mechanical device has an adjustable stroke and exerts a puncturing force independent of operator applied ...

2019

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

Jacques Fellay, Paul Jack Mc Laren

Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have b ...

Public Library Science2013

Ablation of the Tumor Suppressor Histidine Triad Nucleotide Binding Protein 1 is Protective Against Hepatic Ischemia/Reperfusion Injury

The identification of cellular pathways capable of limiting ischemia/reperfusion (I/R) injury remains a frontier in medicine, and its clinical relevance is urgent. Histidine triad nucleotide binding protein 1 (HINT1) is a tumor suppressor that influences a ...

2011

A Perching Mechanism for Micro Aerial Vehicles

Dario Floreano, Roland Siegwart, Mirko Kovac, Jürg Markus Germann

Micro Aerial Vehicles (MAVs) with perching capabilities can be used to efficiently place sensors in aloft locations. A major challenge for perching is to build a lightweight mechanism that can be easily mounted on a MAV, allowing it to perch (attach and de ...

2010