Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Concept

Capillary electrophoresis–mass spectrometry

Publications associées (30)

New analytical tools combining gel electrophoresis and mass spectrometry

Elena Tobolkina

Proteomics has been one of the main projects challenging biological and analytical chemists for many years. The separation, identification and quantification of all the proteins expressed within biological systems remain the main objectives of proteomics. ...

EPFL2014

Mass Spectrometry based Analytical Methods for Proteome Analysis and Redoxomics

Liang Qiao

Proteomics is nowadays one of the most important research topics in life science for understanding many life activities from the molecular level. The objective is to find out proteins or modifications on proteins that regulate biological events, aging, dis ...

EPFL2013

Electrostatic-spray ionization mass spectrometry sniffing for perfume fingerprinting

Hubert Girault, Liang Qiao, Elena Tobolkina

RATIONALE: The perfume market is growing significantly, and it is easy to find imitative fragrances of probably all types of perfume. Such imitative fragrances are usually of lower quality than the authentic ones, creating a possible threat for perfume com ...

Wiley-Blackwell2013

Practical Considerations for Improving the Productivity of Mass Spectrometry-based Proteomics

Yury Tsybin, Anton Kozhinov, Luca Fornelli, Kristina Srzentic, Unige Anna Laskay

Mass spectrometry (MS) is currently the most sensitive and selective analytical technique for routine peptide and protein structure analysis. Top-down proteomics is based on tandem mass spectrometry (MS/MS) of intact proteins, where multiply charged precur ...

Schweizerische Chemische Gesellschaft2013

Fragmentation methods on the balance: unambiguous top–down mass spectrometric characterization of oxaliplatin–ubiquitin binding sites

Paul Joseph Dyson, Yury Tsybin, Christian Hartinger

The interaction between oxaliplatin and the model protein ubiquitin (Ub) was investigated in a top-down approach by means of high-resolution electrospray ionization mass spectrometry (ESI-MS) using diverse tandem mass spectrometric (MS/MS) techniques, incl ...

Springer-Verlag2012

Mass Spectrometry Based Analysis and Bioanalysis

Hongyan Bi

MS (mass spectrometry) has been developed as an important analytical tool to study large molecules including polymer macromolecules and proteins. Its instrumentation technique including ionization methods, mass analyzer and detector systems has been greatl ...

EPFL2010

Miniaturized analytical systems for mass spectrometry-based protein studies

Mélanie Abonnenc

Current proteomic strategies depend strongly on the development of analytical methodologies and instrumentation. In parallel to the development of mass spectrometry (MS) - based proteomic workflows, microfluidic devices emerged in this field as a flexible ...

EPFL2009

Asymmetrical flow field-flow fractionation coupled to multi-angle light scattering detector: optimization of crossflow rate, carrier characteristics and injected mass in alginate separation

Vera Slaveykova-Startcheva

The coupling of the flow field flow fractionation to differential refractive index (DRI) and multi-angle laser light scattering detectors is a powerful tool for characterizing charged polysaccharides such as alginate. However, the correct interpretation of ...

2007

Microfluidic front-end technologies for protein electrospray mass spectrometry

Niels Erik Lion

In the present work, a polymer microfabricated microsprayer is characterised and tested for the mass spectrometric analysis of biomolecules, in particular in the context of protein mass spectrometry and proteomics. As the core of this work deals with analy ...

EPFL2006

Micro ion analysis

Xiaoxia Bai

Due to the growing interest on micro total analytical system (μTAS), fast analysis of small amount samples with high throughout is highly desired. Conventional separation techniques, such as Liquid Chromatography, show a great potential for miniaturisation ...

EPFL2004