Biomechanical, morphological and zero-stress state characterization of jugular vein remodeling in arteriovenous fistulas for hemodialysis

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Autorepression of yeast Hsp70 cochaperones by intramolecular interactions involving their J-domains

Paolo De Los Rios, Bruno Claude Daniel Fauvet, Adélaïde Alice Mohr, Mathieu Rebeaud, Satyam Tiwari

The 70 kDa heat shock protein (Hsp70) chaperones control protein homeostasis in all ATP-containing cellular compartments. J-domain proteins (JDPs) coevolved with Hsp70s to trigger ATP hydrolysis and catalytically upload various substrate polypeptides in ne ...

Elsevier Science Inc2024

Quantifying the Unknown: Data-Driven Approaches and Applications in Energy Systems

Paul Scharnhorst

In light of the challenges posed by climate change and the goals of the Paris Agreement, electricity generation is shifting to a more renewable and decentralized pattern, while the operation of systems like buildings is increasingly electrified. This calls ...

EPFL2024

Compliance-matching vascular grafts with personalization potential

Georgios Rovas

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

EPFL2023

Research data supporting 'Fiber pumps for wearable fluidic systems'

Herbert Shea, Vito Cacucciolo, Michael James Henry Smith

The dataset supporting 'Fiber pumps for wearable fluidic systems', published in Science in March 2023. In this work, we present a fluidic pump in the form of a flexible and stretchable tube. These tubes - or 'fiber pumps' - can generate significant fluidic ...

2023

Reduced order modeling of parametrized pulsatile blood flows: Hematocrit percentage and heart rate

Ricardo Reyes Sotomayor

This paper numerically evaluates the accuracy and performance of a stabilized finite element Reduced Order Modelling (ROM) approach that is designed to simulate pulsatile blood flows. The method is able to estimate fluid flow parametric solutions of intere ...

PERGAMON-ELSEVIER SCIENCE LTD2023

1805-1898 Census Records of Lausanne : a Long Digital Dataset for Demographic History

Isabella Di Lenardo, Rémi Guillaume Petitpierre, Lucas Arnaud André Rappo, Marion Kramer

This historical dataset stems from the project of automatic extraction of 72 census records of Lausanne, Switzerland. The complete dataset covers a century of historical demography in Lausanne (1805-1898), which corresponds to 18,831 pages, and nearly 6 mi ...

Zenodo2023

Toward a common standard for data and specimen provenance in life sciences

Marco Mattavelli, Anna Marsano

Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly influenced by t ...

WILEY2023

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Sokratis Anagnostopoulos

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

Nature Portfolio2023

On Artificial Intelligence and Manipulation

Marcello Ienca

The increasing diffusion of novel digital and online sociotechnical systems for arational behavioral influence based on Artificial Intelligence (AI), such as social media, microtargeting advertising, and personalized search algorithms, has brought about ne ...

SPRINGER2023

Cardiac output estimated from an uncalibrated radial blood pressure waveform: validation in an in-silico-generated population

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas

Background: Cardiac output is essential for patient management in critically ill patients. The state-of-the-art for cardiac output monitoring bears limitations that pertain to the invasive nature of the method, high costs, and associated complications. Hen ...

FRONTIERS MEDIA SA2023

Validating functional redundancy with mixed generative adversarial networks

Quoc Viet Hung Nguyen, Thành Tâm Nguyên, Thanh Trung Huynh

Data redundancy has been one of the most important problems in data-intensive applications such as data mining and machine learning. Removing data redundancy brings many benefits in efficient data updating, effective data storage, and error-free query proc ...

ELSEVIER2023