Publications related to High-dimensional non-convex landscapes and gradient descent dynamics

Related publications (24)

Integrating AI across the Chemistry Discovery Cycle: Advancing Sustainable Chemistry through Digital Methods

The chemical industry faces mounting pressure to develop more sustainable processes while accelerating innovation to address climate challenges. Traditional discovery approaches in chemistry follow an iterative cycle: forming hypotheses about new molecules ...

EPFL2025

AMCG: a graph dual atomic-molecular conditional molecular generator

Andrea Cavalli

Drug design is both a time consuming and expensive endeavour. Computational strategies offer viable options to address this task; deep learning approaches in particular are indeed gaining traction for their capability of dealing with chemical structures. A ...

IOP Publishing2024

Towards improving full-length ribosome density prediction by bridging sequence and graph-based representations

Mohan Vamsi Nallapareddy, Pierre Vandergheynst, Felix Naef, Cédric Gobet, Francesco Craighero

Translation elongation plays an important role in regulating protein concentrations in the cell, and dysregulation of this process has been linked to several human diseases. In this study, we use data from ribo-seq experiments to model ribosome densities, ...

PMLR2024

Machine learning-aided generative molecular design

Philippe Schwaller, Jeff Guo

Machine learning has provided a means to accelerate early-stage drug discovery by combining molecule generation and filtering steps in a single architecture that leverages the experience and design preferences of medicinal chemists. However, designing mach ...

Nature Portfolio2024

TEE4EHR: Transformer event encoder for better representation learning in electronic health records

David Atienza Alonso, Anisoara Ionescu, Hojjat Karami

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing values in certain clinical variables is not at random but depends on the decisi ...

2024

Floorplan Isovist Dataset

Mikhael Johanes

This dataset was created as part of the PhD project Machine Understanding of Architectural Space: From Analytical to Generative Applications at EPFL Media and Design Lab (LDM). It was derived from the Cubicasa5K dataset. The dataset contains preprocessed d ...

Zenodo2024

Supplementary files for Machine learning for histological annotation and quantification of cortical layers

Olivier Burri, Julie Meystre

Creators Meystre Julie Olivier Burri Contributors Jean Jacquemier Description This dataset contains 7 QuPath projects. The raw data images linked to these projects and located in other Zenodo datasets need to be downloaded as well. The raw data contains im ...

Zenodo2024

An Efficient Machine Learning Model for Lightning Localization via Lightning-Induced Voltages on Transmission Lines

Farhad Rachidi-Haeri, Marcos Rubinstein, Hamidreza Karami

In this paper, three machine learning (ML)-based approaches—XGBoost, Artificial Neural Network (ANN), and Random Forest algorithms—are compared for the localization of lightning through the analysis of lightninginduced voltages on power transmission lines. ...

URSI – International Union of Radio Science2024

Self-supervised learning of wrist-worn daily living accelerometer data improves the automated detection of gait in older adults

Anisoara Ionescu

Progressive gait impairment is common among aging adults. Remote phenotyping of gait during daily living has the potential to quantify gait alterations and evaluate the effects of interventions that may prevent disability in the aging population. Here, we ...

Nature Research2024

Learning to Remove Cuts in Integer Linear Programming

Volkan Cevher, Grigorios Chrysos, Efstratios Panteleimon Skoulakis

Cutting plane methods are a fundamental approach for solving integer linear programs (ILPs). In each iteration of such methods, additional linear constraints (cuts) are introduced to the constraint set with the aim of excluding the previous fractional opti ...

2024

ScoreNet: Learning Non-Uniform Attention and Augmentation for Transformer-Based Histopathological Image Classification

Jean-Philippe Thiran, Seyedbehzad Bozorgtabar, Thomas Grégoire Stegmüller, Antoine Jérôme Spahr

Progress in digital pathology is hindered by high-resolution images and the prohibitive cost of exhaustive localized annotations. The commonly used paradigm to categorize pathology images is patch-based processing, which often incorporates multiple instanc ...

IEEE COMPUTER SOC2023

New tools for phase segmentation and denoising of analytical STEM data for enhanced chemical sensitivity, applied to Earth mantle research

Hui Chen, Hui Chen

This thesis is dedicated to developing innovative methodologies that improve elemental quantification in scanning transmission electron microscopy (STEM) using energy-dispersive X-ray spectroscopy (EDXS). The primary motivation stems from a geochemistry pr ...

EPFL2023

TwoResNet: Two-level resolution neural network for traffic forecasting on freeway networks

Nikolaos Geroliminis, Semin Kwak

Traffic forecasting problems of freeway networks are heavily tackled by deep learning methods because it requires learning highly complex correlations between variables both in time and space. Adopting a graph convolutional network (GCN) becomes a standard ...

IEEE2022

A machine learning method for real-time numerical simulations of cardiac electromechanics

Alfio Quarteroni

We propose a machine learning-based method to build a system of differential equations that approximates the dynamics of 3D electromechanical models for the human heart, accounting for the dependence on a set of parameters. Specifically, our method permits ...

ELSEVIER SCIENCE SA2022

Deep learning diagnostic and risk-stratification pattern detection for COVID-19 in digital lung auscultations: clinical protocol for a case-control and prospective cohort study

Martin Jaggi, Mary-Anne Hartley

Background Lung auscultation is fundamental to the clinical diagnosis of respiratory disease. However, auscultation is a subjective practice and interpretations vary widely between users. The digitization of auscultation acquisition and interpretation is a ...

2021

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Bruno Emanuel Ferreira De Sousa Correia, Pablo Gainza Cirauqui

The optimization of therapeutic antibodies is time-intensive and resource-demanding, largely because of the low-throughput screening of full-length antibodies (approximately 1 x 10(3) variants) expressed in mammalian cells, which typically results in few o ...

NATURE RESEARCH2021

Deep Neural Network to Accurately Predict Left Ventricular Systolic Function Under Mechanical Assistance

Simone Deparis, Luca Pegolotti

Characterizing left ventricle (LV) systolic function in the presence of an LV assist device (LVAD) is extremely challenging. We developed a framework comprising a deep neural network (DNN) and a 0D model of the cardiovascular system to predict parameters o ...

FRONTIERS MEDIA SA2021

ActiveMoCap: Optimized Viewpoint Selection for Active Human Motion Capture

Pascal Fua, Mathieu Salzmann, Helge Jochen Rhodin, Sena Kiciroglu

The accuracy of monocular 3D human pose estimation depends on the viewpoint from which the image is captured. While freely moving cameras, such as on drones, provide control over this viewpoint, automatically positioning them at the location which will yie ...

IEEE2020

Kernel Regression for Graph Signal Prediction in Presence of Sparse Noise

Pascal Frossard, Arun Venkitaraman

In presence of sparse noise we propose kernel regression for predicting output vectors which are smooth over a given graph. Sparse noise models the training outputs being corrupted either with missing samples or large perturbations. The presence of sparse ...

IEEE2019

Finite strain FFT-based non-linear solvers made simple

Thomas Willem Jan de Geus

Computational micromechanics and homogenization require the solution of the mechanical equilibrium of a periodic cell that comprises a (generally complex) microstructure. Techniques that apply the Fast Fourier Transform have attracted much attention as the ...

Elsevier2017