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A microfluidic device for protein preconcentration based on the electrokinetic trapping principle is proposed. It comprises a Nafion strip which is simply cut from a commercially available membrane and integrated into a polydimethylsiloxane (PDMS) microfluidic structure using a guiding channel. By applying low voltage (1000 of fluorescently labeled bovine serum albumin (BSA) within a few minutes. Moreover, a numerical study of the preconcentration effect is presented to microscopically understand the phenomenon in our type of device.
Christoph Merten, Leonie Kolmar, Xiaoli Ma, Hongxing Hu
Martinus Adela Maria Gijs, Thomas Lehnert