Publication

A microbial-derived succinylated bile acid to safeguard liver health

Kristina Schoonjans, Alessia Perino, Hadrien Charles Edouard Demagny
2024
Journal Articles

Abstract

In this issue of Cell, Nie and co-authors report that the microbe-derived bile acid (BA) 3-succinylated cholic acid protects against the progression of metabolic dysfunction-associated liver disease. Intriguingly, its protective mechanism does not involve traditional BA signaling pathways but is instead linked to the proliferation of the commensal microbe Akkermansia muciniphila.

Official source

https://infoscience.epfl.ch/entities/publication/5955fc4d-52bc-426c-b998-6918d09c97d6

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A microbial-derived succinylated bile acid to safeguard liver health

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