Publication

Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes

Jean-Claude Bünzli, Caroline Vandevyver, Anne-Sophie Chauvin, Steve Comby
2007
Journal Articles

Abstract

Water-soluble triple-stranded [Ln2(L)3] helicates have been successfully tested as imaging probes in human cervical adenocarcinoma cells (HeLa), the complex being not toxic and clearly staining their cytoplasm in a concentrationdependent manner.

Official source

https://infoscience.epfl.ch/entities/publication/e83702c9-4712-425a-ad8f-2501ca889cfa

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Jean-Claude Bünzli, Caroline Vandevyver, Anne-Sophie Chauvin, Steve Comby
2007
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/e83702c9-4712-425a-ad8f-2501ca889cfa

About this result

Related concepts (11)

Cervical cancer

Cervical cancer is a cancer arising from the cervix. It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. Early on, typically no symptoms are seen. Later symptoms may include abnormal vaginal bleeding, pelvic pain or pain during sexual intercourse. While bleeding after sex may not be serious, it may also indicate the presence of cervical cancer. Human papillomavirus infection (HPV) causes more than 90% of cases; most who have had HPV infections, however, do not develop cervical cancer.

Cervical intraepithelial neoplasia

Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix. CIN most commonly occurs at the squamocolumnar junction of the cervix, a transitional area between the squamous epithelium of the vagina and the columnar epithelium of the endocervix. It can also occur in vaginal walls and vulvar epithelium.

Pap test

The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), cervical smear (BE), cervical screening (BE), or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or colon (in both men and women). Abnormal findings are often followed up by more sensitive diagnostic procedures and, if warranted, interventions that aim to prevent progression to cervical cancer.

Related publications (11)

Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes

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Telecytologic diagnosis of cervical smears for triage of self-sampled human papillomavirus–positive women in a resource-limited setting: concept development before implementation

Cis-regulatory effect of HPV integration is constrained by host chromatin architecture in cervical cancers

Smartphone-Based Visual Inspection with Acetic Acid: An Innovative Tool to Improve Cervical Cancer Screening in Low-Resource Setting