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Synaptotagmin increases the dynamic range of synapses by driving Ca2+ - evoked release and by clamping a near-linear remaining Ca2+ sensor

Related publications (29)

Raytraverse: Navigating the Lightfield to Enhance Climate-Based Daylight Modeling

Marilyne Andersen, Jan Wienold, Stephen William Wasilewski

We propose a new method for climate-based daylight modeling (CBDM) based on simulating and evaluating only the most important features. By adaptively sampling the temporal lightfield that describes daylight in buildings, our method escapes the curse of dim ...

2021

Recent advances in superconducting nanowire single-photon detector technology for exoplanet transit spectroscopy in the mid-infrared

Simone Frasca

The Origins Space Telescope mission concept includes an exoplanet transit spectrometer that requires detector arrays with ultrahigh pixel-to-pixel stability. Superconducting nanowire single-photon detectors, or SNSPDs, have the potential to meet these stri ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2021

ANTIGONE: A Programmable Energy-Efficient Current Digitizer for an ISFET Wearable Sweat Sensing System

Maher Kayal, François Krummenacher, Evgenia Voulgari

This article describes the design and the characterization of the ANTIGONE (ANalog To dIGital cONvErter) ASIC (Application Specific Integrated Circuit) built in AMS 0.35 m technology for low dc-current sensing. This energy-efficient ASIC was specifically d ...

2021

Homeostatic regulation of axonal Kv1.1 channels accounts for both synaptic and intrinsic modifications in the hippocampal CA3 circuit

Mickael Maurice Zbili

Homeostatic plasticity of intrinsic excitability goes hand in hand with homeostatic plasticity of synaptic transmission. However, the mechanisms linking the two forms of homeostatic regulation have not been identified so far. Using electrophysiological, im ...

National Academy of Sciences2021

Ultrasound Imaging: From Physical Modeling to Deep Learning

Dimitris Perdios

Among the medical imaging modalities, ultrasound (US) imaging is one of the safest, most widespread, and least expensive method used in medical diagnosis. In the past decades, several technological advances enabled the advent of ultrafast US imaging, an ac ...

EPFL2021

High dynamic range image sharing with privacy protection

Touradj Ebrahimi, Evgeniy Upenik, Pol Fernandez Marti

Sharing pictures has become a very popular practice among consumers. Most recent cameras, displays, and smartphones can capture and display images in high dynamic range and wide colour gamut, contributing to an increase of this type of content. It is a wel ...

SPIE2020

Quanta burst photography

Claudio Bruschini, Edoardo Charbon, Arin Can Ülkü, Shantanu Gupta, Mohit Gupta

Single-photon avalanche diodes (SPADs) are an emerging sensor technology capable of detecting individual incident photons, and capturing their time-of-arrival with high timing precision. While these sensors were limited to singlepixel or low-resolution dev ...

2020

Multimodal Response to Copper Binding in Superoxide Dismutase Dynamics

David Lyndon Emsley

Copper/zinc superoxide dismutase (SOD) is a homodimeric metalloenzyme that has been extensively studied as a benchmark for structure-function relationships in proteins, in particular because of its implication in the familial form of the neurodegenerative ...

AMER CHEMICAL SOC2020

Learning stereo reconstruction with deep neural networks

Stepan Tulyakov

Stereo reconstruction is a problem of recovering a 3d structure of a scene from a pair of images of the scene, acquired from different viewpoints. It has been investigated for decades and many successful methods were developed. The main drawback of these ...

EPFL2020