Molecular mechanisms governing Ca2+ regulation of evoked and spontaneous release

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Acyl protein thioesterase APT2 interacts with membranes via its charged beta-tongue, becomes palmitoylated by ZDHHC3/7 and deforms the bilayer to extract substrate acyl chains. APT2 deacylation leads to its membrane release and degradation. ...

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Molecular mechanisms governing Ca2+ regulation of evoked and spontaneous release

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