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Diffusion Spectrum Imaging Shows the Structural Basis of Functional Cerebellar Circuits in the Human Cerebellum In Vivo

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Simulation-based Anomaly Detection and Damage Localization: An application to Structural Health Monitoring

Jan Sickmann Hesthaven, Caterina Bigoni

We propose a simulation-based decision strategy for the proactive maintenance of complex structures with a particular application to structural health monitoring (SHM). The strategy is based on a data-driven approach which exploits an offline-online decomp ...

2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Simply Structured Wearable Triboelectric Nanogenerator Based on a Hybrid Composition of Carbon Nanotubes and Polymer Layer

Jürgen Brugger

Triboelectric nanogenerators (TENGs) have proven to be a robust power source for efficiently converting environmental mechanical energy into electricity. Triboelectric technology experienced substantial growth in the past few years, especially in the field ...

KOREAN SOC PRECISION ENG2020

Numerical methods for structural anomaly detection using model order reduction and data-driven techniques

Caterina Bigoni

The objective of this thesis is to provide a mathematical and computational framework for the proactive maintenance of complex systems with a particular application to structural health monitoring (SHM). SHM techniques rely primarily on sensor responses to ...

EPFL2020

Reactions of pyrrole, imidazole, and pyrazole with ozone: kinetics and mechanisms

Urs von Gunten, Peter Rudolf Tentscher, Sung Eun Lim

Five-membered nitrogen-containing heterocyclic compounds (azoles) belong to potential moieties in complex structures where transformations during ozonation can occur. This study focused on the azole-ozone chemistry of pyrrole, imidazole, and pyrazole as mo ...

ROYAL SOC CHEMISTRY2020

Brain-spine interface technologies to alleviate gait deficits after Parkinson's disease

Flavio Raschella

Gait and balance deficits are motor disabilities that typically develop late in the progression of Parkinson's disease (PD). These deficits are thought to be the result of dysregulated neural activity in the cortico-basal ganglia-thalamic-cortical motor lo ...

EPFL2019

Consensus Paper: Experimental Neurostimulation of the Cerebellum

Traian Popa

The cerebellum is best known for its role in controlling motor behaviors. However, recent work supports the view that it also influences non-motor behaviors. The contribution of the cerebellum towards different brain functions is underscored by its involve ...

Springer2019

Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

Hongxia Lei, Yohan Van de Looij

Systemic hypoxia-ischemia (HI) often occurs during preterm birth in human. HI induces injuries to hinder brain cells mainly in the ipsilateral forebrain structures. Such HI injuries may cause lifelong disturbances in the distant regions, such as the contra ...

2019

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Marco Capogrosso, Stanisa Raspopovic, Francesco Maria Petrini, Jacopo Rigosa

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019

An Optimal Planning Framework to Deploy Self-Reconfigurable Modular Robots

Auke Ijspeert, Mehmet Hasan Mutlu, Simon Lukas Hauser, Alexandre Bernardino, Hala Khodr

Self-reconfiguration is a hard problem due to the high dimensionality of self-reconfigurable modular systems. Searchbased approaches offer complete and optimal solutions. However, naive search algorithms cannot directly solve self-reconfiguration tasks in ...

2019

Phase resolved characterization of nanoscale features in optical microstructures

Michail Symeonidis

In this study, we apply interferometric microscopy to study the phase, alongside the intensity, of the light field transmitted through a wide variety of samples. Additionally, we conduct those interferometric measurements at different wavelengths within th ...

EPFL2019

Experimental Insights Into Fault Reactivation in Gouge-Filled Fault Zones

Carolina Giorgetti, Francesco Tesei

Faults in the brittle crust constitute preexisting weakness zones that can be reactivated depending on their friction, orientation within the local stress field, and stress field magnitude. Analytical approaches to evaluate the potential for fault reactiva ...

AMER GEOPHYSICAL UNION2019

Surface-based characteristics of the cerebellar cortex visualized with ultra-high field MRI

Wietske Van der Zwaag, Cristina Granziera, Gunnar Krüger, Guillaume Bonnier, Kieran O'Brien, Yohan Boillat

Although having a relatively homogeneous cytoarchitectonic organization, the cerebellar cortex is a heterogeneous region characterized by different amounts of myelin, iron and protein expression profiles. In this study, we used quantitative T1 and T2* mapp ...

2018