Publication

Process development for the optical resolution of phenylalanine by means of chymotrypsin in a liquid-liquid-solid three-phase reaction system

Albert Renken
1992
Book Chapters

Abstract

The stereospecific hydrolysis of phenylalanine esters by chymotrypsin can avantageously be undertaken in aq.-org. 2-phase systems. The partitioning of the deprotonated form of the substrate changes the pH characteristics of the reaction system drastically. It even permits ester hydrolysis to be performed without pH control. Thus, plug flow reactors may be used in the case of immobilized chymotrypsin. However, severe mass transfer limitations are encountered when a fixed bed reactor is fed with an emulsion. [on SciFinder (R)]

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https://infoscience.epfl.ch/entities/publication/d31f5129-8132-4fbf-b4ed-51eac35611c6

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Albert Renken
1992
Book Chapters

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/d31f5129-8132-4fbf-b4ed-51eac35611c6

About this result

Related concepts (17)

Plug flow reactor model

The plug flow reactor model (PFR, sometimes called continuous tubular reactor, CTR, or piston flow reactors) is a model used to describe chemical reactions in continuous, flowing systems of cylindrical geometry. The PFR model is used to predict the behavior of chemical reactors of such design, so that key reactor variables, such as the dimensions of the reactor, can be estimated.

Laminar flow reactor

A laminar flow reactor (LFR) is a type of chemical reactor that uses laminar flow to control reaction rate, and/or reaction distribution. LFR is generally a long tube with constant diameter that is kept at constant temperature. Reactants are injected at one end and products are collected and monitored at the other. Laminar flow reactors are often used to study an isolated elementary reaction or multi-step reaction mechanism. Laminar flow reactors employ the characteristics of laminar flow to achieve various research purposes.

Chemical reactor

A chemical reactor is an enclosed volume in which a chemical reaction takes place. In chemical engineering, it is generally understood to be a process vessel used to carry out a chemical reaction, which is one of the classic unit operations in chemical process analysis. The design of a chemical reactor deals with multiple aspects of chemical engineering. Chemical engineers design reactors to maximize net present value for the given reaction.

Related publications (9)

Process development for the optical resolution of phenylalanine by means of chymotrypsin in a liquid-liquid-solid three-phase reaction system

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