Publication

Orchestration of pluripotent stem cell genome reactivation during mitotic exit

David Michael Suter, Cédric Deluz, Ludovica Vanzan, Silja Michelle Placzek
2025

Abstract

Cell identity maintenance faces many challenges during mitosis, as most DNA-binding proteins are evicted from DNA and transcription is virtually abolished. How cells maintain their identity through division and faithfully re-initiate gene expression during mitotic exit is unclear. Here, we develop a novel reporter system enabling cell cycle synchronization-free separation of pluripotent stem cells in temporal bins of

Official source

https://infoscience.epfl.ch/entities/publication/c5706d1d-d257-45d3-9f63-bb4d8d7ab4e6

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Orchestration of pluripotent stem cell genome reactivation during mitotic exit

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