Publications related to Radiobiology of Radiosurgery for Neurosurgeons

Related publications (13)

Cryogenic Operation of Silicon Photomultiplier Arrays

Olivier Schneider, Guido Haefeli, Frédéric Blanc, Lesya Shchutska, Federico Ronchetti, Radoslav Marchevski, Gianluca Zunica, Esteban Curras Rivera

The LHCb experiment at CERN has been upgraded for the Run 3 operation of the Large Hadron Collider (LHC). A new concept of tracking detector based on Scintillating Fibres (SciFi) read out with multichannel silicon photomultipliers (SiPMs) was installed dur ...

IOP Publishing Ltd2025

Simultaneous Irradiation and Testing for Radiation Damage Evaluation in Actively Biased SiPMs and Other Devices

Chiara Perrina, Jennifer Maria Frieden

A portable opto-electronic device test bench together with a neutron irradiation setup at Reactor Argentino 1 (RA-1) facility in Buenos Aires (Argentina) is presented. The irradiation with neutrons is performed to reproduce the expected damage the devices ...

Institute of Electrical and Electronics Engineers Inc.2024

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

Matthias Lütolf, Freddy Radtke, Nicolas Antoine Vincent Broguiere, Luis Francisco Lorenzo Martin, Tania Hübscher, Amber Dawn Bowler, Jakob Josef Langer, Lucie Carrié Tillard

Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures 1-3 . This has enabled better modelling of low-complexity cancer ...

NATURE PORTFOLIO2024

Smart chemistry for traceless release of anticancer therapeutics

Xile Hu, Li Tang, Céline Jasmin Prange

In the design of delivery strategies for anticancer therapeutics, the controlled release of intact cargo at the destined tumor and metastasis locations is of particular importance. To this end, stimuli-responsive chemical linkers have been extensively inve ...

Elsevier Sci Ltd2023

Multi-syndrome, multi-gene risk modeling for individuals with a family history of cancer with the novel R package PanelPRO

Christine Choirat, Gavin Keenyan Lee

Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models focus on a few specific syndromes; however, recent evidence from ...

2021

Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers

Melody Swartz, Douglas Hanahan, Nadine Fournier, Mélanie Louise Tichet, Stephan Wullschleger, Gabriele Galliverti

Cancers induced by human papillomaviruses (HPV) should be responsive to immunotherapy by virtue of expressing the immunogenic oncoproteins E6/E7. However, advanced forms of cervical cancer, driven by HPV, are poorly responsive to immune response-enhancing ...

AMER ASSOC CANCER RESEARCH2020

Influence of Halo Implantations on the Total Ionizing Dose Response of 28-nm pMOSFETs Irradiated to Ultrahigh Doses

Christian Enz

In this paper, the total ionizing dose (TID) response of a commercial 28-nm high-k CMOS technology at ultrahigh doses is measured and discussed. The degradation of pMOSFETs depends not only on the channel width but also on the channel length. Short-channel ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2019

Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors

Douglas Hanahan, Gabriele Galliverti

High-risk human papillomavirus (HPV) are responsible for genital and oral cancers associated with the expression of the E6/E7 HPV oncogenes. Therapeutic vaccines targeting those oncogenes can only partially control tumor progression, highlighting the neces ...

2019

Ganciclovir derivatives for modulating innate and adaptive immunity and for use in immunotherapy

Hilal Lashuel, Ritwik Burai

Compositions and methods for modulating innate and adaptive immunity and for use in immunotherapy are disclosed. In particular, the invention relates to novel ganciclovir derivatives and methods of using them for the treatment of immune-related disorders, ...

2017

Role of RIP4 in lung adenocarcinoma differentiation

Jawahar Kopparam

Various studies have attributed NF-kB activation to promote KRAS mediated non-small cell lung cancer progression. In order to identify key genes regulating NF-kB activation and cell survival in lung adenocarcinoma, a synthetic lethal partner screen for KRA ...

EPFL2016

Early detection of human glioma sphere xenografts in mouse brain using diffusion MRI at 14.1 T

Rolf Gruetter, Hongxia Lei

Glioma models have provided important insights into human brain cancers. Among the investigative tools, MRI has allowed their characterization and diagnosis. In this study, we investigated whether diffusion MRI might be a useful technique for early detecti ...

Wiley-Blackwell2016

A sensitive x-ray phase contrast technique for rapid imaging using a single phase grid analyzer

Peter Modregger

Phase contrast x-ray imaging (PCXI) is a promising imaging modality, capable of sensitively differentiating soft tissue structures at high spatial resolution. However, high sensitivity often comes at the cost of a long exposure time or multiple exposures p ...

Optical Society of America2013

Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro

Georges Wagnières, Tanja Gabrecht

To detect bronchial carcinoma by autofluorescence, we measured the spectra of tumor and normal tissue in situ, in an in vivo model and in vitro by fiber optic spectrometer and two-dimensional resolved microspectroscopy. The in situ measurements were perfor ...

Elsevier2008