Publication

Bioanalytical procedure to detect membrane receptor activation

Horst Arthur Vogel, Horst Pick
2010
Patents

Abstract

The invention concerns a method for screening compound interaction with transmembrane receptors involved in cellular signal transduction, preferably with G protein coupled receptors, by adding the compound to be analyzed into a medium comprising native inverted vesicles with at least one said transmembrane receptor whose native intracellular side is located on the outer surface of the inverted vesicle.

Official source

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Bioanalytical procedure to detect membrane receptor activation

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