Publication

Synchrotron microangiography with no contrast agent

Giorgio Margaritondo, Amela Groso
2004
Journal Articles

Abstract

Coherent x-rays from synchrotron sources are increasingly used in non-conventional radiological techniques ('phase-contrast' radiology). Our experiments demonstrate that by using white (unmonochromatic) radiation and a time-resolving system, it is possible to image microscopic details of moving blood vessels in different live animals without using any contrast agent. The images have excellent contrast plus unprecedented spatial resolution for microangiography (< 10 mum). This result is likely to impact many different areas of biological and medical research and of diagnostic radiology.

Official source

https://infoscience.epfl.ch/entities/publication/b7c2178d-bdcf-4284-a753-0f097cbf7483

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Giorgio Margaritondo, Amela Groso
2004
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/b7c2178d-bdcf-4284-a753-0f097cbf7483

About this result

Related concepts (27)

Phase-contrast imaging

Phase-contrast imaging is a method of that has a range of different applications. It measures differences in the refractive index of different materials to differentiate between structures under analysis. In conventional light microscopy, phase contrast can be employed to distinguish between structures of similar transparency, and to examine crystals on the basis of their double refraction. This has uses in biological, medical and geological science.

Phase-contrast X-ray imaging

Phase-contrast X-ray imaging or phase-sensitive X-ray imaging is a general term for different technical methods that use information concerning changes in the phase of an X-ray beam that passes through an object in order to create its images. Standard X-ray imaging techniques like radiography or computed tomography (CT) rely on a decrease of the X-ray beam's intensity (attenuation) when traversing the sample, which can be measured directly with the assistance of an X-ray detector.

Radiographer

Radiographers, also known as radiologic technologists, diagnostic radiographers and medical radiation technologists are healthcare professionals who specialise in the imaging of human anatomy for the diagnosis and treatment of pathology. Radiographers are infrequently, and almost always erroneously, known as x-ray technicians. In countries that use the title radiologic technologist they are often informally referred to as techs in the clinical environment; this phrase has emerged in popular culture such as television programmes.

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Synchrotron microangiography with no contrast agent

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