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Lab-grown 'mini-colons' enable the simulation of colorectal tumor dynamics and the high-resolution study of interactions with cells from the tumor's native microenvironment. These next-generation organoids offer a wealth of new experimental opportunities, propelling the frontiers of cancer modeling in multiple directions.
Matthias Lütolf, Nathalie Brandenberg, Nicolas Antoine Vincent Broguiere, Krisztian Homicsko, Lucie Carrié Tillard, Sylke Höhnel, François Réal Rivest, Devanjali Dutta, Damien Saugy