Next-generation patient models for colorectal cancer research

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Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models able to readily assess the effectiveness of immunotherapeutic treatments ...

The intestine is a complex organ that promotes digestion, extracts nutrients, participates in immune surveillance, maintains critical symbiotic relationships with microbiota and affects overall health(1). The intesting has a length of over nine metres, alo ...

The development of microfluidics has led to significant improvements in many areas of in vitro diagnostics. This thesis proposes the use of microfluidic device technology in the field of anatomic pathology, leading to faster and more accurate tissue-based ...

Next-generation patient models for colorectal cancer research

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Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed colorectal cancer tumoroids

Organization of the human intestine at single-cell resolution

Microfluidic staining technology and automated image processing for fast and accurate tissue-based diagnostics

Roles of telomeres and telomerase in cancer