On the role of water density fluctuations in the inhibition of a proton channel

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On the role of water density fluctuations in the inhibition of a proton channel

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From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Structural heterogeneity of the ion and lipid channel TMEM16F

NMR and MS reveal characteristic metabolome atlas and optimize esophageal squamous cell carcinoma early detection

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Development of cysteine cathepsin inhibitors combined with cell type-specific delivery for the treatment of B-cell lymphoma and solid tumors

6-diazo-5-oxo-l-norleucine prodrugs

The conceptual foundations of innate immunity: Taking stock 30 years later

Predicting protein interactions using geometric deep learning on protein surfaces

Computational drug development for membrane protein targets

Ru(II)-Arene Complexes of Curcumin and Bisdesmethoxycurcumin Metabolites

Tumor-educated Gr1+CD11b+cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity

Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

Next-Generation Modeling of Cancer Using Organoids

Androgen Receptor Signaling in in vivo models of Estrogen Receptor-positive Breast Cancer and Normal Breast Epithelium

Machine learning-aided generative molecular design

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions

Engineering novel protein interactions with therapeutic potential using deep learning-guided surface design

Antibodies expand the scope of angiotensin receptor pharmacology

Augmenting large language models with chemistry tools

A chemical biology approach to decipher chromatin ubiquitylation by RNF168