Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Members of the bacterial species Vibrio cholerae are known both as prominent constituents of marine environments and as the causative agents of cholera, a severe diarrheal disease. While strains responsible for cholera have been extensively studied over th ...

Pregnancy brings about profound changes in the mammary gland to prepare for lactation, yet immunocyte changes that accompany this rapid remodeling are incompletely understood. We comprehensively analyzed mammary T cells, revealing a marked increase in CD4+ ...

Aims/hypothesistRNAs play a central role in protein synthesis. Besides this canonical function, they were recently found to generate non-coding RNA fragments (tRFs) regulating different cellular activities. The aim of this study was to assess the involveme ...

Three-dmensonal (3)-prntng technology s nstrumental n creatng devces for bologcal applcatons, ncludng the explotaton of cold atmospherc plasma (CAP). CAP, a partally onzed gas that functons at ambent temperatures, serves as a safe, nexpensve, and effectve ...

Being responsible for almost 15 % of the deaths globally, infectious diseases (IDs) are considered as a major health challenge, which was lately emphasized by the COVID-19 pandemic once again. Data form COVID pandemic revealed that early and timely detecti ...

Chimeric antigen receptor (CAR) T-cell therapy continues to struggle in reaching its full potential in solid tumors, largely due to the tumor microenvironment (TME) where various small molecules induce immunosuppressive signaling in CAR T-cells. Two key mo ...

Acute kidney failure and chronic kidney disease are global health issues steadily rising in incidence and prevalence. Animal models on a single genetic background have so far failed to recapitulate the clinical presentation of human nephropathies. Here, we ...

Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains

Chat with Graph Search

On meta-analytic models and the effect of hydroxychloroquine use in COVID-19

Exploring Mobile Genetic Elements in Vibrio cholerae

Mammary Intraepithelial Lymphocytes and Intestinal Inputs Shape T Cell Dynamics in Lactogenesis

tRNA-derived fragments in T lymphocyte-beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice

3-prnted devces for optmzed generaton of cold atmospherc plasma to mprove decontamnaton of surfaces from respratory pathogens

Advances in biosensor technologies for infectious diseases detection

Boosting CAR T-cell therapy through G-protein signal rewiring

Mitochondrial and NAD plus metabolism predict recovery from acute kidney injury in a diverse mouse population

Modeling of Future COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Rates and Nonpharmaceutical Intervention Scenarios - United States, April-September 2021