Low-Intensity Focused Ultrasound Neuromodulation for Stroke Recovery: A Novel Deep Brain Stimulation Approach for Neurorehabilitation?

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Optimization frameworks for bespoke sensory encoding in neuroprosthetics

Silvestro Micera, Solaiman Shokur, Franklin Leong

Restoring natural sensation via neuroprosthetics relies on the possibility of encoding complex and nuanced information. For example, an ideal brain–machine interface with sensory feedback would provide the user with sensation about movement, pressure, curv ...

AIP Publishing2025

Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons

Armando Romani

Understanding the brain requires studying its multiscale interactions from molecules to networks. The increasing availability of large-scale datasets detailing brain circuit composition, connectivity, and activity is transforming neuroscience. However, int ...

SOC NEUROSCIENCE2024

In vivo recording of visually evoked potentials with novel full diamond ECoG implants

Diego Ghezzi, Eleonora Borda

Implantable neuroprosthetic devices such as electrocorticography (ECoG) and intracortical microelectrodes have the potential to restore neurological functions in disabled individuals. They constitute the direct interface with the body and require long term ...

2024

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

Jean François Pierre Laurens, Auke Ijspeert, Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Jocelyne Bloch, Giuseppe Schiavone, Elvira Pirondini, Jordan Squair, Eduardo Martin Moraud, Léonie Asboth, Robin Jonathan Demesmaeker, Tomislav Milekovic, Jimmy James Ravier, Jean-Baptiste Mignardot, Flavio Raschella, Simon Borgognon, Alice Julie Bruel, Carmina Andrea Galvez Solano, Camille Georgette Marie Le Goff-Mignardot, Charlotte Marie Jacques Moerman, David Allenson Borton, Grégory Didier Dumont, Sergio Daniel Hernandez, Nicolò Macellari, Shiqi Sun

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dor ...

Nature Portfolio2023