Can you Teach Cell Biology using Computer Simulations?

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This thesis contributes to the modelling of multivariate rare events by combining extreme value theory and graphical modelling. The central theme involves structural equation models (SEMs), which are powerful tools used to express causal extremal dependenc ...

Creators Meystre Julie Olivier Burri Contributors Jean Jacquemier Description This dataset contains 7 QuPath projects. The raw data images linked to these projects and located in other Zenodo datasets need to be downloaded as well. The raw data contains im ...

This letter presents a whole-body robot control method for exploring and probing a given region of interest. The ergodic control formalism behind such an exploration behavior consists of matching the time-averaged statistics of a robot trajectory with the ...

The main theme of my thesis will be to use neuro-muscular modeling techniques to study locomotion of terrestrial mammals. Locomotion is the ability of animals to interact with the environment to propel themselves in space. It involves co-ordination and pre ...

We propose a machine learning-based method to build a system of differential equations that approximates the dynamics of 3D electromechanical models for the human heart, accounting for the dependence on a set of parameters. Specifically, our method permits ...

This article proposes a new logic synthesis and verification paradigm based on circuit simulation. In this paradigm, high quality, expressive simulation patterns are pregenerated to be reused in multiple runs of optimization and verification algorithms, re ...

In this paper we address an unresolved problem in the numerical modeling of cardiac electromechanics, that is the onset of numerical oscillations due to the dependence of force generation models on the fibers shortening velocity. A way to avoid numerical o ...

Human fetal progenitor tenocytes (hFPT) produced in defined cell bank systems have recently been characterized and qualified as potential therapeutic cell sources in tendon regenerative medicine. In view of further developing the manufacture processes of s ...

Coupling DNA sensing to the initiation of immune responses necessitates auxiliary control mechanisms to avoid autoimmunity. A key factor is the exonuclease TREX1, which antagonizes DNA-mediated activation of cGAS. Two studies, by Mohr et al. (2021) and Zho ...

The kidney's inherent complexity has made identifying cell-specific pathways challenging, particularly when temporally associating them with the dynamic pathophysiology of acute kidney injury (AKI). Here, we combine renal cell-specific luciferase reporter ...

Can you Teach Cell Biology using Computer Simulations?

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Structural equation models for multivariate extremes

Supplementary files for Machine learning for histological annotation and quantification of cortical layers

Whole-Body Ergodic Exploration With a Manipulator Using Diffusion

A computational modeling approach to study the neuromechanics of terrestrial locomotion

A machine learning method for real-time numerical simulations of cardiac electromechanics

A Simulation-Guided Paradigm for Logic Synthesis and Verification

An oscillation-free fully staggered algorithm for velocity-dependent active models of cardiac mechanics

Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine

The spatial organization of cGAS-TREX1 interactions

Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice