A model for 3D deformation and reconstruction of contractile microtissues

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Localized sources of morphogens, called signalling centres, play a fundamental role in coordinating tissue growth and cell fate specification during organogenesis. However, how these signalling centres are established in tissues during embryonic developmen ...

Bending-active elastica beam is a structural configuration that is based on the elastic deformation of an initially straight beam. This deformation occurs when horizontal displacements are applied to a sliding support, causing the beam to bend into an arch ...

Suspended epitaxial gallium nitride (GaN) on silicon (Si) photonic crystal devices suffer from large residual tensile strain, especially for long waveguides, because fine structures tend to crack due to large stress. By introducing spring-like tethers, des ...

Organoids, miniature tissues generated from self-organizing stem cells within three-dimensional (3D) extracellular matrices (ECM), have opened up exciting possibilities for in vitro studies of complex physiological processes. A key factor in the success of ...

When two objects slide against each other, wear and friction occur at their interface. The accumulation of wear forms what is commonly referred to as a ``third-body''. Understanding third-body evolution has significant applications in industry, where contr ...

Fiber-polymer composites consist of a polymer matrix and reinforcing fibers made of various materials. These composites exhibit exceptional properties, such as a high strength-to-weight ratio and excellent corrosion resistance, which has led to their incre ...

Earthquakes i.e. frictional ruptures, are commonly described by singular solutions of shear crack motions. These solutions assume a square root singularity order around the rupture tip and a constant shear stress value behind it, implying scale-independent ...

Traditional cell cultures have long been fundamental to biological research, offering an alternative to animal models burdened by ethical constraints and procedural intricacies, often lacking relevance to human physiology and disease. Moreover, their inabi ...

This work introduces a new methodology to predict the fatigue life of viscoelastic materials by considering the creep effect on fatigue behavior under the concurrent effects of stress level, stress ratio, and temperature. The model established based on the ...

Chondrocytes within articular cartilage possess the capacity to perceive and react to signals generated by the typical load-bearing actions of daily life, such as walking or running. Articular cartilage is predominantly oriented toward compression-based fu ...

Peroxisomes are eukaryotic organelles that are essential for multiple metabolic pathways, including fatty acid oxidation, degradation of amino acids, and biosynthesis of ether lipids. Consequently, peroxisome dysfunction leads to pediatric-onset neurodegen ...

This data package supports the publication 'Complexity of crack front geometry enhances toughness of brittle solids' by Xinyue Wei, Chenzhuo Li, Cían McCarthy, and John M. Kolinski Nature physics (2024) - https://doi.org/10.1038/s41567-024-02435-x DOI: 1 ...

Most codes of practice adopt a semi probabilistic design approach for the dimensioning and assessment of structures. Accordingly, structural safety is ensured by performing limit state verifications using design values determined with adequately calibrated ...

In the last decade, organoid technology has become a cornerstone in cancer research. Organoids are long-term primary cell cultures, usually of epithelial origin, grown in a three-dimensional (3D) protein matrix and a fully defined medium. Organoids can be ...

Fatigue damage in materials results in localized strain at the microstructural level. In many engineering components of the cooling circuits of nuclear power plants, where austenitic steels are used, the material experiences multiaxial cyclic loading, eith ...

Metal plasticity is an inherently multiscale phenomenon due to the complex long-range field of atomistic dislocations that are the primary mechanism for plastic deformation in metals. Atomistic/Continuum (A/C) coupling methods are computationally efficient ...

Porous rocks have long been the focus of intense research driven by their importance in our society as host to our most essential resources (oil, gas, water, geothermal energy, etc), yet their rheology remains poorly understood. With increasing depth, poro ...

Three-dimensional topological semimetals have emerged as strong candidates to probe new fundamental physical phenomena that could be exploited to develop next generation electronics. However, many aspects of their electronic properties remain unclear. Thi ...

Offshore pipelines that transport hydrocarbons under high pressure and high temperature are usually thermally insulated to maintain an elevated temperature and prevent any heat loss to the surroundings. However, the temperatures at the outer-wall of the pi ...

Kirigami, the ancient technique of paper cutting, has been successfully applied to enhance the stretchability and ductility of nanoscale graphene. However, existing experimentally realized graphene kirigami (GK) are created by introducing parallel cuts, ex ...

A model for 3D deformation and reconstruction of contractile microtissues

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Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

Short-term behavior of glass fiber-polymer composite bending-active elastica beam under service load application

Strain engineering and strain measurement by spring tethers on suspended epitaxial GaN-on-Si photonic crystal devices

Engineering hydrogel microenvironments for epithelial organoid culture

Modeling friction and wear using an adaptive discrete-continuum coupling

Two-dimensional quasi-static delamination in composite laminates under Mode-I and Mode-II conditions

Frictional weakening leads to unconventional singularities during dynamic rupture propagation

Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

A novel fatigue life prediction methodology based on energy dissipation in viscoelastic materials, synergistic effects of stress level, stress ratio, and temperature

Enhancing Chondrocyte Biosynthetic Activities: Harnessing the Power of Loading-Induced Evolved Temperature

Fluorescent fatty acid conjugates for live cell imaging of peroxisomes

Dataset for "Complexity of crack front geometry enhances toughness of brittle solids"

Influence of model uncertainty and long term deformations in action effects calculation in reinforced concrete structures

Next-Generation Modeling of Cancer Using Organoids

Microscopic Digital Image Correlation Analysis of Strain Distributions in Stainless Steel 316L Induced by Multiaxial Cyclic Loading

Lattice Green's function method for Atomistic/Continuum coupling

Bounding the localized to ductile transition in porous rocks: implications for geo-reservoirs

Strain Gradients and Magnetoresistance in Microstructured 3D Topological Semi-metals

Drained Clay-Pipe Interface Resistance at Low Normal Stresses and Elevated Temperatures

Deformation response of highly stretchable and ductile graphene kirigami under uniaxial and biaxial tension