Integration of Metabolic, Regulatory and Signaling Networks Towards Analysis of Perturbation and Dynamic Responses

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Transporters of the SLC25 mitochondrial carrier superfamily bridge cytoplasmic and mitochondrial metabolism by channeling metabolites across mitochondrial membranes and are pivotal for metabolic homeostasis. Despite their physiological relevance as gatekee ...

Carbamazepine (CBZ) and Hg are widespread and persistent micropollutants in aquatic environments. Both pollutants are known to trigger similar toxicity mechanisms, e.g. reactive oxygen species (ROS) production. Here, their effects were assessed in the zebr ...

Approximately 2 billion people worldwide and a significant part of the domestic livestock are infected with soil-transmitted helminths, of which many establish chronic infections causing substantial eco-nomic and welfare burdens. Beside intensive research ...

Integration of Metabolic, Regulatory and Signaling Networks Towards Analysis of Perturbation and Dynamic Responses

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Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

Method and system for determining intracellular mediators' activity

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

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Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

AMP-activated Protein Kinase (AMPK): New molecular insights and novel downstream targets

Modulation of Subcellular Redox Homeostasis with Trialkylphosphines

Dissecting the role of the mitochondrial carrier SLC25A47

Metabolic, cellular and defense responses to single and co-exposure to carbamazepine and methylmercury in Dreissena polymorpha

Acetate, a metabolic product of Heligmosomoides polygyrus, facilitates intestinal epithelial barrier breakdown in a FFAR2-dependent manner