Cyclization and annulation reactions of nitrogen-substituted cyclopropanes and cyclobutanes

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Examples for applications of nitrous oxide in organic synthesis remain rare up until today. First mayor contributions of our group were published in 2012, when nitrous oxide was successfully captured by N-heterocyclic carbenes. Subsequent studies investiga ...

Amino alcohols, cyclopropanes and nitriles are privileged structural motifs found in the scaffold of natural products and bioactive compounds. In addition, they are versatile building blocks in organic chemistry. The development of new and increasingly eff ...

Nitrous oxide is a potential diazo transfer reagent, but its applications in organic chemistry are scarce. Here, we show that triazolopyridines and triazoloquinolines are formed in the reactions of metallated 2-alkylpyridines or 2-alkylquinolines with N2O. ...

The development of new catalytic methods for organic synthesis is a critical endeavour in order to obviate the economic and ecological drawbacks of stoichiometric organic synthesis. While catalysis can offer significant advantages in terms of atom-economy, ...

To endow metal-free materials with the high catalytic activity that is typically featured by a metal-based catalyst is yet a constant pursuit in the field of catalytic chemistry. In this work, novel functional biochars (DCNs) were prepared from wheat straw ...

For the past two decades, linear free energy scaling relationships and volcano plots have seen frequent use as computational tools that aid in understanding and predicting the catalytic behavior of heterogeneous and electrocatalysts. Based on Sabatier's pr ...

Understanding the mechanisms behind chemical transformations is key to developing improved catalytic systems. To this end, operando spectroscopy has contributed significantly to the advancement of our molecular view of many reactions at the heart of the ch ...

The development of a sequential copper-catalyzed oxy-alkynylation/intramolecular [4+2] cycloaddition of allenes and arenes was investigated at first. This one-pot protocol allowed the construction of complex polycylic architectures with high efficiency fro ...

Elegant asymmetric synthesis of hasubanan alkaloids have been developed over the past decades. However, a divergent approach leading to all three sub-classes of this family of natural products remains unknown. We report herein the realization of such an en ...

The valorisation of the plant biopolymer lignin is now recognised as essential to enabling the economic viability of the lignocellulosic biorefining industry. In this context, the "lignin-first" biorefining approach, in which lignin valorisation is conside ...

Diamines are essential building blocks for the synthesis of agrochemicals, drugs, and organic materials, yet their synthesis remains challenging, as both nitrogens need to be differentiated and diverse substitution patterns (1,2, 1,3, or 1,4) are required. ...

Carboxymethyl cellulose/copper oxide-nickel oxide (CMC/CuO-NiO) nanocomposite beads were prepared by facile, simple and environmentally friendlymethod. Initially, CuO-NiOwas prepared and applied for the catalytic reduction of 4-nitrophenol (4-NP). The resu ...

Pincer ligated coordination complexes of base metals have shown remarkable catalytic activity for hydrogenation/dehydrogenation of CO2. The recently reported MeNCH2CH2(Pr-i(2))Co(I)PNP-pincer complex was shown to exhibit substantially higher catalytic ...

The electrochemical CO2 reduction reaction (CO2RR) is envisioned to play a significant role in achieving carbon neutrality while contributing to storing renewable energies. Cu-based materials are among the most promising electrocatalysts. However, 16 diffe ...

Cyclization and annulation reactions of nitrogen-substituted cyclopropanes and cyclobutanes

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Isolation, Characterisation and Reactivity of N-Heterocyclic Diazoolefins

New Strategies for the Functionalization of Alkenes Exploiting Tethering Chemistry and Ring Strain

Nitrous oxide as a diazo transfer reagent: the synthesis of triazolopyridines

Developing the Catalytic Applications of 1,3,2-Diazaphospholenes

Construction of Functional Superhydrophobic Biochars as Hydrogen Transfer Catalysts for Dehydrogenation of N-Heterocycles

The Genesis of Molecular Volcano Plots

Time-Resolved Spectroscopy of Selective Catalytic Reduction (SCR) Catalysts under Transient Conditions

New Vinylation and Alkynylation Strategies with Hypervalent Iodine Reagents and Diazo Compounds

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

Guidelines for performing lignin-first biorefining

Diamine Synthesis via the Nitrogen-Directed Azidation of sigma- and pi-C-C Bonds

Carboxymethyl cellulose nanocomposite beads as super-efficient catalyst for the reduction of organic and inorganic pollutants

Explaining the Advantageous Impact of Tertiary versus Secondary Nitrogen Center on the Activity of PNP-Pincer Co(I)-Complexes for Catalytic Hydrogenation of CO2

Cu/Metal Oxide Hybrid Nanocrystals as Electrocatalysts for the CO2 Reduction Reaction