Publication

Nitrous oxide as a diazo transfer reagent: the synthesis of triazolopyridines

Kay Severin, Farzaneh Fadaei Tirani, Iris Roswitha Landman
2021
Journal Articles

Abstract

Nitrous oxide is a potential diazo transfer reagent, but its applications in organic chemistry are scarce. Here, we show that triazolopyridines and triazoloquinolines are formed in the reactions of metallated 2-alkylpyridines or 2-alkylquinolines with N2O. The reactions can be performed under mild conditions and give synthetically interesting triazoles in moderate to good yields.

Official source

https://infoscience.epfl.ch/entities/publication/f1365d16-e9de-407b-b501-9a83679211f5

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Nitrous oxide as a diazo transfer reagent: the synthesis of triazolopyridines

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