Hardware/Software Coevolution of Genome Programs and Cellular Processors

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Thermal Design of a Medium Voltage Modular Multilevel Converter Cell

Drazen Dujic, Yanick Patrick Frei

This paper presents the cooling concept for a medium voltage modular multilevel converter cell. To optimize power density, the metallic enclosure is used to dissipate the heat generated by semiconductor losses, while maintaining maximum temperatures below ...

New York2023

Imprecise Store Exceptions

Babak Falsafi, Mathias Josef Payer, Siddharth Gupta, Yunho Oh, Yuanlong Li, Abhishek Bhattacharjee, Qingxuan Kang

Precise exceptions are a cornerstone of modern computing as they provide the abstraction of sequential instruction execution to programmers while accommodating microarchitectural optimizations. However, increasing compute capabilities in deep memory hierar ...

ACM2023

Computational conceptual design — typological exploration of spatial truss systems through optimization

Corentin Jean Dominique Fivet, Jonas Warmuth

Exploring a wide range of design options is crucial for every sound conceptual design process. In the conventional structural design workflow, optimization techniques are generally employed to generate well-performing design options. However, focusing only ...

International Association for Shell and Spatial Structures (IASS)2023

Leveraging the Snap Buckling of Bistable Magnetic Shells to Design a Refreshable Braille Dot

Pedro Miguel Nunes Pereira de Almeida Reis, Tian Chen, Arefeh Abbasi, Bastien Freddy Gustave Aymon

A design concept is proposed for the building block, a dot, of programmable braille readers utilizing bistable shell buckling, magnetic actuation, and pneumatic loading. The design process is guided by Finite Element simulations, which are initially valida ...

Wiley2023

Interactive design with optimum matchmaking of reused structural elements – a software implementation

Corentin Jean Dominique Fivet, Jan Friedrich Georg Brütting, Jonas Warmuth

Structural systems are a significant contributor to buildings’ embodied carbon and reusing structural elements in new load-bearing applications is one strategy to reduce this impact. However, integrating this approach into existing design workflows without ...

International Association for Shell and Spatial Structures (IASS)2023

Collective data-based drawings A common ground for adaptive contributive design

The laboratory ALICE (Atelier de la Conception de l’Espace) at the École Polytechnique Fédérale de Lausanne (EPFL) advances a comprehensive approach to data-based drawing oriented towards architectural and urban co-design processes. This drawing methodolog ...

2023

Computational Conceptual Design – Typological Exploration Of Spatial Truss Systems Through Optimization

Corentin Jean Dominique Fivet, Jonas Warmuth

Exploring a wide range of relevant design options from the outset is crucial for every sound conceptual design process. Optimization techniques are generally employed to generate well-performing structural design options. However, focusing only on performa ...

2023

Landscapes of DNA Mechanics and Genomes

Thomas Antonin Zwahlen

The local physical properties - such as shape and flexibility - of the DNA double-helix is today widely believed to be influenced by nucleic acid sequence in a non-trivial way. Furthermore, there is strong evidence that these properties play a role in many ...

EPFL2023

Targeting molecular surfaces to engineer novel protein-based immunogens and inhibitors

Sarah Wehrle

Proteins are the basic building blocks necessary for the operation and regulation of virtually all functions in living organisms. Over millions of years, evolution has created a vast repertoire of proteins finely tuned to execute their biological functions ...

EPFL2022