Publication

PEG-based gels for the release of proteins and the encapsulation of cells

1993
Conference Papers

Abstract

A PEG-based polymer matrix is developed within which biol. macromols. and living mammalian cells could be easily dispersed. Constraints placed upon such a matrix by a desire that it be generally processable in the presence of biol. macromols. and living cells include limiting temps. to physiol. or lower, working in oxygenated environments, avoiding exposure to cytotoxic monomers, avoiding exposure to org. solvents, and avoiding chem. reactions that readily modify functional groups found in proteins, such as carboxyls and amines. [on SciFinder (R)]

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1993
Conference Papers

Abstract

Official source

Related concepts (24)

T cell

T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells.

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell.

T helper cell

The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system. They aid the activity of other immune cells by releasing cytokines. They are considered essential in B cell antibody class switching, breaking cross-tolerance in dendritic cells, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils.

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PEG-based gels for the release of proteins and the encapsulation of cells

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