Native learning ability and not age determines the effects of brain stimulation

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The invention provides fusion protein comprising a SCAN domain bearing member of a zinc finger-containing protein, a fragment or variant thereof and a catalytically inactive RNA- guided endonuclease or a DNA adenine methyltransferase. Preferably, the fusio ...

Accurately measuring behavior is critical to understanding brain function. While traditional behavioral analysis has relied on human observation and manual processing, advances in machine learning and computer vision have begun to automate the field. This ...

Epilepsy is a common chronic neurological disorder that causes recurring seizures and affects more than 50 million people worldwide. Implantable medical devices (IMDs) are regarded as effective tools to cure patients who suffer from refractory epilepsy. Se ...

Tuberculosis (TB) is a major global health challenge, with approximately 1.4 million deaths per year. There is still a need to develop novel treatments for patients infected with Mycobacterium tuberculosis (Mtb). There have been many large-scale phenotypic ...

Development of neural interface and brain-machine interface (BMI) systems enables the treatment of neurological disorders including cognitive, sensory, and motor dysfunctions. While neural interfaces have steadily decreased in form factor, recent developme ...

Long acquisition times preclude the application of multiecho spin echo (MESE) sequences for myelin water fraction (MWF) mapping in daily clinical practice. In search of alternative methods, previous studies of interest explored the biophysical modeling of ...

Understanding how learners engage with learning technologies, and its relation with their learning, is crucial to the design of effective learning interventions. Assessing the learners’ state however, is non-trivial. Research suggests that performance is n ...

Even though there has been numerous works performed based on electrochemical impedance spectroscopy (EIS) of perovskite solar cells (PSCs), however, many aspects of the obtained EI spectra are yet to be fully grasped. Moreover, the change of these spectra ...

Designing and implementing online or digital learning material is a demanding task for teachers. This is even more the case when this material is used for more engaged forms of learning, such as inquiry learning. In this article, we give an informed accoun ...

Our brain constantly receives and integrates a flow of sensory and motor information that shapes the way our body is represented. Several experimental approaches have been proposed to alter the body representation, by manipulating exteroceptive or interoce ...

Objective Hand amputation is a highly disabling event, which significantly affects quality of life. An effective hand replacement can be achieved if the user, in addition to motor functions, is provided with the sensations that are naturally perceived whil ...

Recent studies have shown that direct nerve stimulation can be used to provide sensory feedback to hand amputees. The intensity of the elicited sensations can be modulated using the amplitude or frequency of the injected stimuli. However, a comprehensive c ...

Native learning ability and not age determines the effects of brain stimulation

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Scan-based fusion proteins for modulating gene expression and methods of use

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Hardware Implementation of Digital Signal Processing Algorithms for Programmable Epilepsy Control Systems

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