Atrial natriuretic peptideAtrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene. Natriuretic peptides (ANP, BNP, and CNP) are a family of hormone/paracrine factors that are structurally related. The main function of ANP is causing a reduction in expanded extracellular fluid (ECF) volume by increasing renal sodium excretion. ANP is synthesized and secreted by cardiac muscle cells in the walls of the atria in the heart.
Valve of coronary sinusIn the anatomy of the heart, the valve of the coronary sinus (also called the Thebesian valve, after Adam Christian Thebesius) is a valve located at the orifice of the coronary sinus where the coronary sinus drains into the right atrium. It prevents blood from flowing backwards into the coronary sinus during contraction of the heart. The valve of the coronary sinus is a thin, semilunar (half-moon-shaped) valve located on the anteroinferior part of the opening into the right atrium.
Foramen secundumThe foramen secundum, or ostium secundum is a in the septum primum, a precursor to the interatrial septum of the human heart. It is not the same as the foramen ovale, which is an opening in the septum secundum. Interatrial septum#Development The foramen secundum () is formed from small perforations that develop in the septum primum. The septum primum is a that grows down between the single primitive atrium of the developing heart to separate it into left and right atria.
Absolute geometryAbsolute geometry is a geometry based on an axiom system for Euclidean geometry without the parallel postulate or any of its alternatives. Traditionally, this has meant using only the first four of Euclid's postulates. The term was introduced by János Bolyai in 1832. It is sometimes referred to as neutral geometry, as it is neutral with respect to the parallel postulate. The first four of Euclid's postulates are now considered insufficient as a basis of Euclidean geometry, so other systems (such as Hilbert's axioms without the parallel axiom) are used instead.
Projective geometryIn mathematics, projective geometry is the study of geometric properties that are invariant with respect to projective transformations. This means that, compared to elementary Euclidean geometry, projective geometry has a different setting, projective space, and a selective set of basic geometric concepts. The basic intuitions are that projective space has more points than Euclidean space, for a given dimension, and that geometric transformations are permitted that transform the extra points (called "points at infinity") to Euclidean points, and vice-versa.
Euclidean geometryEuclidean geometry is a mathematical system attributed to ancient Greek mathematician Euclid, which he described in his textbook on geometry, Elements. Euclid's approach consists in assuming a small set of intuitively appealing axioms (postulates) and deducing many other propositions (theorems) from these. Although many of Euclid's results had been stated earlier, Euclid was the first to organize these propositions into a logical system in which each result is proved from axioms and previously proved theorems.
Threshold potentialIn electrophysiology, the threshold potential is the critical level to which a membrane potential must be depolarized to initiate an action potential. In neuroscience, threshold potentials are necessary to regulate and propagate signaling in both the central nervous system (CNS) and the peripheral nervous system (PNS). Most often, the threshold potential is a membrane potential value between –50 and –55 mV, but can vary based upon several factors.
Hyperbolic geometryIn mathematics, hyperbolic geometry (also called Lobachevskian geometry or Bolyai–Lobachevskian geometry) is a non-Euclidean geometry. The parallel postulate of Euclidean geometry is replaced with: For any given line R and point P not on R, in the plane containing both line R and point P there are at least two distinct lines through P that do not intersect R. (Compare the above with Playfair's axiom, the modern version of Euclid's parallel postulate.) The hyperbolic plane is a plane where every point is a saddle point.
Sodium channelSodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily of cation channels. They are classified into 2 types: In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials. These channels go through three different states called resting, active and inactive states.
Progressive musicProgressive music is music that attempts to expand existing stylistic boundaries associated with specific genres of music. The word comes from the basic concept of "progress", which refers to advancements through accumulation, and is often deployed in the context of distinct genres, with progressive rock being the most notable example. Music that is deemed "progressive" usually synthesizes influences from various cultural domains, such as European art music, Celtic folk, West Indian, or African.
Channel blockerA channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell. Channel blocking is conducted by different types of molecules, such as cations, anions, amino acids, and other chemicals. These blockers act as ion channel antagonists, preventing the response that is normally provided by the opening of the channel.
Hypertrophic cardiomyopathyHypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This results in the heart being less able to pump blood effectively and also may cause electrical conduction problems. People who have HCM may have a range of symptoms. People may be asymptomatic, or may have fatigue, leg swelling, and shortness of breath.
