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Leveraging social media data and large language models for understanding public health behaviours in the context of infectious diseases and vaccination

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Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Jacques Fellay

Life-threatening "breakthrough"cases of critical COVID-19 are attributed to poor or waning antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting auto-Abs neutralizing type I IFNs underlie at least 15% of critical COVID-1 ...

2023

Relative Effects of the Hospital Readmissions Reduction Program on Hospitals That Serve Poorer Patients

Christine Choirat

Importance: Hospitals that serve poorer populations have higher readmission rates. It is unknown whether these hospitals effectively lowered readmission rates in response to the Hospital Readmissions Reduction Program (HRRP). Objective: To compare pre-post ...

2019

Exploring new therapeutic strategies for Huntington's Disease

Wanqiu Hu

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by an extended poly-glutamine tract in the huntingtin gene (HTT). Despite intensive efforts in understanding its pathogenesis over the decades, effective treatments for HD remain u ...

EPFL2014

BactImAS: a platform for processing and analysis of bacterial time-lapse microscopy movies

Zeljka Maglica

Background: The software available to date for analyzing image sequences from time-lapse microscopy works only for certain bacteria and under limited conditions. These programs, mostly MATLAB-based, fail for microbes with irregular shape, indistinct cell d ...

Biomed Central Ltd2014

Reassessment of the 2010-2011 Haiti cholera outbreak and rainfall-driven multiseason projections

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari, Lorenzo Righetto

Mathematical models can provide key insights into the course of an ongoing epidemic, potentially aiding real-time emergency management in allocating health care resources and by anticipating the impact of alternative interventions. We study the ex post rel ...

2012