A high-performance compact electromagnetic actuator for a PMMA ball-valve micropump

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Thermal and pH Sensitive Composite Membrane for On-Demand Drug Delivery by Applying an Alternating Magnetic Field

Jürgen Brugger, Giovanni Boero, Xiao Sheng Zhang, Ya Wang

Implantable drug delivery systems that can realize a scheduled drug release according to the needs of patients would be highly beneficial for the treatment of chronic diseases and cancer. Here, micrometer‐sized hydrogel particles with both thermal and pH s ...

2020

Comb Transducer for Generation of SH0 Mode in Crystalline Piezoelectric Membrane

Soumya Yandrapalli

It is shown that the comb IDT (CT) can efficiently excite SH0 mode in piezoelectric membrane of suitable orientation. The transducer has pitch equal to the wavelength (p=lambda) and the electrode size is half of the wavelength. As compared to conventional ...

IEEE2020

Crank arrangement for driving a mechanical oscillator

Romain Roger Henri Gillet, Simon Nessim Henein, Billy Nussbaumer

Crank arrangement (1) for driving a pin-driven two degrees? of freedom mechanical oscillator (5), comprising:- a crank element (7) arranged to be rotationally driven about an axis of rotation (19) by means of a mechanical source of energy (M),- a crank slo ...

2020

Mitochondrial cristae modeled as an out-of-equilibrium membrane driven by a proton field

Anne-Florence Raphaëlle Bitbol

As the places where most of the fuel of the cell, namely, ATP, is synthesized, mitochondria are crucial organelles in eukaryotic cells. The shape of the invaginations of the mitochondria inner membrane, known as a crista, has been identified as a signature ...

2020

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation

Suliana Manley, Christian Sieben

Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill ...

2020

Transient Electronics for Smart Biodegradable Medical Implants

Matthieu Jean Michel Rüegg

Bioresorbable implantable medical devices show great potential for applications requiring medical care over well-defined periods of time. Such implants naturally degrade and resorb in the body, which eliminates adverse long-term effects or the need for a s ...

EPFL2020

Nonlinear buckling behavior of a complete spherical shell under uniform external pressure and homogenous natural curvature

Matteo Pezzulla

In this work, we consider the stability of a spherical shell under combined loading from a uniform external pressure and a homogenous natural curvature. Nonmechanical stimuli, such as one that tends to modify the rest curvature of an elastic body, are prev ...

AMER PHYSICAL SOC2020

Feedback-free microfluidic oscillator with impinging jets

Philippe Renaud, François Gallaire, Arnaud Bertsch, Alessandro Bongarzone, Margaux Catherine Marie Duchamp

The present paper describes a microfluidic oscillator based on facing impinging jets and operating in laminar flow conditions. Using appropriate microchannel configurations, pulsatile liquid flows are generated at the microscale from steady and equal inlet ...

2020

Three-dimensional electrodes for dielectrophoretic applications

Kevin Keim

This thesis reports the use of metal-coated three-dimensional SU-8 electrodes for dielectrophoretic bio sensing and particle manipulation applications. Placing free standing three-dimensional electrodes in microfluidic channels, electric fields can be appl ...

EPFL2020