ReproducibilityReproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method. For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated. There are different kinds of replication but typically replication studies involve different researchers using the same methodology.
Replication crisisThe replication crisis (also called the replicability crisis and the reproducibility crisis) is an ongoing methodological crisis in which the results of many scientific studies are difficult or impossible to reproduce. Because the reproducibility of empirical results is an essential part of the scientific method, such failures undermine the credibility of theories building on them and potentially call into question substantial parts of scientific knowledge.
Publish or perish"Publish or perish" is an aphorism describing the pressure to publish academic work in order to succeed in an academic career. Such institutional pressure is generally strongest at research universities. Some researchers have identified the publish or perish environment as a contributing factor to the replication crisis. Successful publications bring attention to scholars and their sponsoring institutions, which can help continued funding and their careers.
Reproducibility ProjectThe Reproducibility Project: Psychology was a crowdsourced collaboration of 270 contributing authors to repeat 100 published experimental and correlational psychological studies. This project was led by the Center for Open Science and its co-founder, Brian Nosek, who started the project in November 2011. The results of this collaboration were published in August 2015. Reproducibility is the ability to produce the same findings, using the same methodologies as the original work, but on a different dataset (for instance, collected from a different set of participants).
Scientific methodThe scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific method for additional detail.) It involves careful observation, applying rigorous skepticism about what is observed, given that cognitive assumptions can distort how one interprets the observation.
ResearchResearch is "creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole.
American literatureAmerican literature is literature written or produced in the United States of America and in the colonies that preceded it. The American literary tradition thus is part of the broader tradition of English-language literature, but also includes literature of other traditions produced in the United States and in other immigrant languages. Furthermore, a rich tradition of oral storytelling exists amongst Native Americans. The American Revolutionary Period (1775–1783) is notable for the political writings of Benjamin Franklin, Alexander Hamilton, Thomas Paine, and Thomas Jefferson.
British literatureBritish literature is literature from the United Kingdom of Great Britain and Northern Ireland, the Isle of Man, and the Channel Islands. This article covers British literature in the English language. Anglo-Saxon (Old English) literature is included, and there is some discussion of Latin and Anglo-Norman literature, where literature in these languages relate to the early development of the English language and literature. There is also some brief discussion of major figures who wrote in Scots, but the main discussion is in the various Scottish literature articles.
MetascienceMetascience (also known as meta-research) is the use of scientific methodology to study science itself. Metascience seeks to increase the quality of scientific research while reducing inefficiency. It is also known as "research on research" and "the science of science", as it uses research methods to study how research is done and find where improvements can be made. Metascience concerns itself with all fields of research and has been described as "a bird's eye view of science".
Immune systemThe immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinters, distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli.
English literatureEnglish literature is literature written in the English language from the United Kingdom, its Crown Dependencies and Overseas Territories, the Republic of Ireland, the United States, and the countries of the former British Empire. The English language has developed over the course of more than 1,400 years. The earliest forms of English, a set of Anglo-Frisian dialects brought to Great Britain by Anglo-Saxon invaders in the fifth century, are called Old English.
Scientific misconductScientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research. A Lancet review on Handling of Scientific Misconduct in Scandinavian countries provides the following sample definitions, reproduced in The COPE report 1999: Danish definition: "Intention or gross negligence leading to fabrication of the scientific message or a false credit or emphasis given to a scientist" Swedish definition: "Intention[al] distortion of the research process by fabrication of data, text, hypothesis, or methods from another researcher's manuscript form or publication; or distortion of the research process in other ways.
Western literatureWestern literature, also known as European literature, is the literature written in the context of Western culture in the languages of Europe, and is shaped by the periods in which they were conceived, with each period containing prominent western authors, poets, and pieces of literature. The best of Western literature is considered to be the Western canon. The list of works in the Western canon varies according to the critic's opinions on Western culture and the relative importance of its defining characteristics.
Scientific skepticismScientific skepticism or rational skepticism (also spelled scepticism), sometimes referred to as skeptical inquiry, is a position in which one questions the veracity of claims lacking empirical evidence. In practice, the term most commonly references the examination of claims and theories that appear to be beyond mainstream science, rather than the routine discussions and challenges among scientists.
African literatureAfrican literature is literature from Africa, either oral ("orature") or written in African and Afro-Asiatic languages. Examples of pre-colonial African literature can be traced back to at least the fourth century AD. The best-known is the Kebra Negast, or "Book of Kings." A common theme during the colonial period is the slave narrative, often written in English or French for western audiences. Among the first pieces of African literature to receive significant worldwide critical acclaim was Things Fall Apart, by Chinua Achebe, published in 1958.
Drosophila melanogasterDrosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, D. melanogaster continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution.
Medical researchMedical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a preclinical understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine.
EpidemiologyEpidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review).
DrosophilaDrosophila (drəˈsɒfᵻlə,_drɒ-,_droʊ-) is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly.
Evidence-based policyEvidence-based policy is a concept in public policy that advocates for policy decisions to be grounded on, or influenced by, rigorously established objective evidence. This concept presents a stark contrast to policymaking predicated on ideology, 'common sense,' anecdotes, or personal intuitions. The approach mirrors the effective altruism movement's philosophy within governmental circles. The methodology employed in evidence-based policy often includes comprehensive research methods such as randomized controlled trials (RCT).
