Publication

Quadrupolar magnetic actuation of superparamagnetic particles for enhanced microfluidic perfusion

Martinus Gijs, Thomas Lehnert, Yves Moser
2009
Journal Articles

Abstract

We report on the magnetic actuation of superparamagnetic particles in a microfluidic channel. The formation of a highly confined and dynamic plug of particles extending over the cross section of the microchannel is enabled by superposing a static and a time-varying magnetic field. The latter is generated by an electromagnet and focused across the microchannel using microstructured soft magnetic tips. Finite element calculations of the magnetic force distribution do compare well with experiments. Our system allows maximizing the exposure of superparamagnetic particles to a microfluidic flow of interest for integrated lab-on-a-chip applications.

Official source

https://infoscience.epfl.ch/entities/publication/5f223adf-aa33-46f5-8e19-2099b25d0ee9

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Martinus Gijs, Thomas Lehnert, Yves Moser
2009
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/5f223adf-aa33-46f5-8e19-2099b25d0ee9

About this result

Related concepts (20)

Microfluidics

Microfluidics refers to a system that manipulates a small amount of fluids ((10−9 to 10−18 liters) using small channels with sizes ten to hundreds micrometres. It is a multidisciplinary field that involves molecular analysis, biodefence, molecular biology, and microelectronics. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening.

Magnetic field

A magnetic field is a vector field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular to its own velocity and to the magnetic field. A permanent magnet's magnetic field pulls on ferromagnetic materials such as iron, and attracts or repels other magnets.

Droplet-based microfluidics

Droplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes (μl to fl) of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments.

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