Publications related to Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

Related publications (52)

Microfluidic systems for infectious disease diagnostics

Martinus Adela Maria Gijs, Thomas Lehnert

Microorganisms, encompassing both uni- and multicellular entities, exhibit remarkable diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential components for sustaining biological processes across diverse ecosystems, i ...

Royal Soc Chemistry2024

Restoration of sensory information via bionic hands

Silvestro Micera

This Review discusses non-invasive and invasive technologies for conveying artificial sensory feedback through bionic hands. ...

NATURE RESEARCH2023

Distributed flexibility as a cost-effective alternative to grid reinforcement

Christophe Ballif, Nicolas Würsch, Jordan Holweger, Alejandro Pena Bello, Noémie Alice Yvonne Ségolène Jeannin

The deployment of distributed photovoltaics (PV) in low-voltage networks may cause technical issues such as voltage rises, line ampacity violations, and transformer overloading for distribution system operators (DSOs). These problems may induce grid reinfo ...

ELSEVIER2023

Automated image-based generation of finite element models for masonry buildings

Katrin Beyer, Radhakrishna Achanta, Bryan German Pantoja Rosero

To predict the response of masonry buildings to various types of loads, engineers use finite element models, specifically solid-element and macro-element models. For predicting masonry responses to seismic events in particular, equivalent frame models-a su ...

SPRINGER2023

Hydrogel-Encased Photonic Microspheres with Enhanced Color Saturation and High Suspension Stability

Esther Amstad

Regular arrays of colloidal particles can produce striking structural colors without the need for any chemical pigments. Regular arrays of colloidal particles can be processed into microparticles via emulsion templates for use as structural colorants. Phot ...

Amer Chemical Soc2023

Development of next-generation microfluidic systems for enhanced, faster, and cost-effective immunoassays for tissue diagnostics - Ac electrothermal flow & Acoustofluidics

Muaz Salama Abdelmonem Draz

The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...

EPFL2023

Label-free plasmonic microarray for multiplexed analysis of cells and tumor organoids

Yen-Cheng Liu

Investigating the dynamic activities of protein expression and signaling in living organisms is a crucial focus of intense research aimed at elucidating the processes that underlie disease progression and improving treatments and drug development. Resolvin ...

EPFL2023

Decision-making algorithms for learning and adaptation with application to COVID-19 data

Ali H. Sayed

This work focuses on the development of a new family of decision-making algorithms for adaptation and learning, which are specifically tailored to decision problems and are constructed by building up on first principles from decision theory. A key observat ...

ELSEVIER2022

Historical Development and Seismic Performance of Unreinforced Masonry Buildings with Vertical Extensions in the City Centre of Barcelona

Savvas Saloustros

This paper presents the historical development of the vertical extensions of unreinforced masonry buildings in the Eixample district of Barcelona and their impact on the seismic behaviour. Existing masonry buildings of Eixample present significant seismic ...

TAYLOR & FRANCIS INC2022

Transient current technique for charged traps detection in silicon bonded interfaces

Jean-Michel Sallese, Alessandro Mapelli, Didier Bouvet

Wafer bonding is an established technology for the manufacturing of silicon-on-insulator (SOI) substrates, microelectromechanical systems (MEMS) and microfluidic devices. Low temperature direct bonding techniques can be of particular interest for the fabri ...

2019

Graph Neural Networks With Lifting-Based Adaptive Graph Wavelets

Pascal Frossard

Spectral-based graph neural networks (SGNNs) have been attracting increasing attention in graph representation learning. However, existing SGNNs are limited in implementing graph filters with rigid transforms and cannot adapt to signals residing on graphs ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Structure analysis of beta dicalcium silicate via scanning transmission electron microscope (STEM)

Franco Alberto Zunino Sommariva, Qiao Wang

Beta-dicalcium silicate (beta-C2S), one of the main phases in Portland cement clinker, offers some promising overviews regarding CO2 and energy savings potential compared to alite. Understanding the crystalline structure and reactive sites on beta-C2S surf ...

ELSEVIER SCI LTD2022

Resonant optical trapping in hollow photonic crystal cavities and its potential use for bacterial characterisation

Rita Therisod

During the last decade, the development of optofluidic chips has become a large field of research. The integration of nano and microstructures with microfluidics layers allowed for the miniaturisation of a number of tools traditionally used in laboratories ...

EPFL2019

Engineering Agrobacterium tumefaciens Adhesion to Target Cells

Alix Kim Lan Pham, Alexandre Louis André Persat, Xavier Jean-Yves Pierrat, Zaïnebe Dhirani, Jeremy Pak Hei Wong

Agrobacterium tumefaciens is a plant pathogen commonly repurposed for genetic modification of crops. Despite its versatility, it remains inefficient at transferring DNA to many hosts, including to animal cells. Like many pathogens, physical contact between ...

AMER CHEMICAL SOC2022

Microfluidics-assisted multiplexed biomarker detection for in situ mapping of immune cells in tumor sections

Martinus Adela Maria Gijs, Daniel Migliozzi, Diego Gabriel Dupouy, Benjamin Pelz

Because of the close interaction between tumors and the immune system, immunotherapies are nowadays considered as the most promising treatment against cancer. In order to define the diagnosis and the subsequent therapy, crucial information about the immune ...

2019

An epidermal wearable microfluidic patch for simultaneous sampling, storage, and analysis of biofluids with counterion monitoring

Silvia Demuru, Brince Paul Kunnel

Simultaneous access to different biofluids enables an accurate analysis of multiple analytes, leading to a precision diagnosis and appropriate medication. Additionally, establishing a relationship between various markers in different biofluids and their co ...

ROYAL SOC CHEMISTRY2022

Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study

Fabio Aimi, Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Saska Brajkovic

Breast cancer is a highly heterogeneous disease. The efficacy of tailored therapeutic strategies relies on the precise detection of diagnostic biomarkers by immunohistochemistry (IHC). Therefore, considering the increasing incidence of breast cancer cases, ...

2019

Photochemical Production of Carbon Monoxide from Dissolved Organic Matter: Role of Lignin Methoxyarene Functional Groups

Joanna Maria Houska

Carbon monoxide (CO) is the second most abundant identified product of dissolved organic matter (DOM) photodegradation after CO2, but its formation mechanism remains unknown. Previous work showed that aqueous photodegradation of methoxy-substituted aromati ...

2022

Label-free plasmonic biosensors for real-time live cell analysis

Xiaokang Li

For decades, the understanding of life has been focused on its most fundamental building blocks: molecules. Deciphering the dynamic activities of protein molecules in human cells is of vital significance for fundamental and clinical studies. The minuscule ...

EPFL2019

Could building replacements significantly contribute to seismic vulnerability mitigation at urban scale? Case studies of two typical swiss cities

Pierino Lestuzzi

This paper contains an investigation on the potential decrease of seismic vulnerability related to building replacements for the cities of Sion and Martigny in Switzerland. Those two cities were identified for the present research based on the accuracy of ...

FRONTIERS MEDIA SA2022