Global maps of travel time to healthcare facilities

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Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

Post-translational modifications (PTMs) play a pivotal role in regulating protein structure, interaction, and function. Aberrant PTM patterns are associated with diseases. Moreover, individual PTMs have a complex interaction with each other, known as PTM c ...

Patterns in nature arise from processes interacting across a continuum of spatial scales, where new relationships emerge at each level of investigation. These patterns are nested features encompassing fine-scale local patterns, such as topography and geolo ...

In a context of escalating public health challenges, including the rise of chronic diseases, the impact of climate change, and the COVID-19 pandemic, certain populations bear a disproportionate burden. As a result, there is an urgent need to develop public ...

As the world’s population grows in cities, urban dwellers spend a large amount of time inside their home, making housing health ever more important. Critical for residents’ health, the interactions between indoor residential environments and outdoor enviro ...

This article explores how the logic underlying modal practices tends to modulate the population’s responsiveness to improvements in global transport supply. Based on a quantitative survey conducted in 2018–2019 among the working population of the cantons o ...

The terminology of neurological disorders encompasses a range of serious illnesses (e.g., epilepsy, Alzheimer's disease) leading to morbidity, disability, and stigma. Epilepsy alone affects over 50 million people worldwide, and these figures are rising as ...

Time has always been a central factor in understanding the challenges of daily mobility. For a long time, and still today, methods of economic evaluation of transport projects have monetized time savings so that they can be included in the cost–benefit ana ...

Waste treatment is a complex procedure that comprises multidimensional aspects. The challenges posed by the energy transition and international protocols emphasize the role of waste in its material and energy dimension. With an increasing population and li ...

Dysregulations in cholesterol metabolism are associated with neurodegenerative and vascular pathologies, and dementia. Diet-derived plant sterols (phytosterols) have cholesterol-lowering, anti-inflammatory, and antioxidant properties and may interfere with ...

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

Rural mobility in Africa is an under-researched issue. Rural communities have often suffered from reduced mobility that has hampered their access to essential services and facilities such as education, health care, food, and clean water. In many rural comm ...

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...

Background: Evaluating the impact of health systems on premature mortality across different countries is a very challenging task, as it is hardly possible to disentangle it from the influence of contextual factors such as cultural differences. In this resp ...

Predictive models based on machine learning (ML) offer a compelling promise: bringing clarity and structure to complex natural and social environments. However, the use of ML poses substantial risks related to the privacy of their training data as well as ...

Fine-grained population maps are needed in several domains, like urban planning, environmental monitoring, public health, and humanitarian operations. Unfortunately, in many countries only aggregate census counts over large spatial units are collected, mor ...

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

The largest source of systematic errors in the time-delay cosmography method likely arises from the lens model mass distribution, where an inaccurate choice of model could in principle bias the value of H-0. A Bayesian hierarchical framework has been propo ...

Global maps of travel time to healthcare facilities

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Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions

At what spatial scale does natural selection operate? Using multiscale frameworks to calibrate the effects of environmental factors across landscape continuums

The role of spatial epidemiology to support public health policies : case studies applied to health promotion, noncommunicable and infectious diseases in the canton of Vaud, Switzerland

Housing, street and health: a new systemic research framework

Analysing the potential for modal shiftbased on the logic of modal choice

Real-time Personalized Monitoring of Neurological Disorders on Wearable Systems

Controlling the Activity of Polo-like Kinase 1 with Light

Appropriations and Uses of Travel Time

Decision support methodology for waste-to-value process integration

Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population

A striatal circuit balances learned fear in the presence and absence of sensory cues

Impact of Topography on Rural Cycling Patterns: Case Study of Bugesera District, Rwanda

Impact of population size on early adaptation in rugged fitness landscapes

Real world multimodal assessment of physical behavior change in health and disease

Different health systems-Different mortality outcomes? Regional disparities in avoidable mortality across German-speaking Europe, 1992-2019

Challenging the Assumptions: Rethinking Privacy, Bias, and Security in Machine Learning

Fine-grained population mapping from coarse census counts and open geodata

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

TOCOSMO VIII. A key test of systematics in the hierarchical method of time-delay cosmography