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Publication

Microfluidic device for sample encapsulation and method for operation thereof

Philippe Renaud, Jiande Zhou
2023
Patents

Abstract

The invention relates to a microfluidic device (3) comprising: - an inlet channel (31) having an inlet configured to be operatively connected with a droplet source (2) wherein the inlet channel (31) has a width wi and height hi; and - an outlet channel with at least one outlet channel branch (32) operatively connected with the inlet channel (31) at a passage point (33), said outlet channel (32) having a width wo, wherein the width wo of the at least one outlet channel branch (32) and the height ℎi and the width wi of the inlet channel (31) satisfy a geometrical condition of formula (I), said z > 1.

Official source

https://infoscience.epfl.ch/entities/publication/533fe29c-72e1-42d7-9058-4cfbecd0027b

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Philippe Renaud, Jiande Zhou
2023
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/533fe29c-72e1-42d7-9058-4cfbecd0027b

About this result

Related concepts (11)

Droplet-based microfluidics

Droplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes (μl to fl) of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments.

Microfluidics

Microfluidics refers to a system that manipulates a small amount of fluids ((10−9 to 10−18 liters) using small channels with sizes ten to hundreds micrometres. It is a multidisciplinary field that involves molecular analysis, biodefence, molecular biology, and microelectronics. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening.

Euler method

In mathematics and computational science, the Euler method (also called the forward Euler method) is a first-order numerical procedure for solving ordinary differential equations (ODEs) with a given initial value. It is the most basic explicit method for numerical integration of ordinary differential equations and is the simplest Runge–Kutta method. The Euler method is named after Leonhard Euler, who first proposed it in his book Institutionum calculi integralis (published 1768–1870).

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