Publication

Online detection of baseline variations through torque measurements in isothermal reaction calorimeters

Urs von Stockar, Ian William Marison
1995
Journal Articles

Abstract

In addn. to online detection of events in biotechnol., calorimetry could be used to control processes. In the latter case, a correct and instantaneous heat signal must be available. This would be possible only if a correct evaluation of baseline evolution were possible. In this paper, it is shown that torque measurements are a powerful tool for detecting and correcting baseline shifts and for eliminating external perturbations during cultures of a filamentous bacterium. [on SciFinder (R)]

Official source

https://infoscience.epfl.ch/entities/publication/4c2f169a-3431-4190-bc89-caeae0bb0f9c

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Urs von Stockar, Ian William Marison
1995
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/4c2f169a-3431-4190-bc89-caeae0bb0f9c

About this result

Related concepts (29)

Isothermal titration calorimetry

In chemical thermodynamics, isothermal titration calorimetry (ITC) is a physical technique used to determine the thermodynamic parameters of interactions in solution. It is most often used to study the binding of small molecules (such as medicinal compounds) to larger macromolecules (proteins, DNA etc.) in a label-free environment. It consists of two cells which are enclosed in an adiabatic jacket. The compounds to be studied are placed in the sample cell, while the other cell, the reference cell, is used as a control and contains the buffer in which the sample is dissolved.

Calorimetry

In chemistry and thermodynamics, calorimetry () is the science or act of measuring changes in state variables of a body for the purpose of deriving the heat transfer associated with changes of its state due, for example, to chemical reactions, physical changes, or phase transitions under specified constraints. Calorimetry is performed with a calorimeter. Scottish physician and scientist Joseph Black, who was the first to recognize the distinction between heat and temperature, is said to be the founder of the science of calorimetry.

Differential scanning calorimetry

Differential scanning calorimetry (DSC) is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. Both the sample and reference are maintained at nearly the same temperature throughout the experiment. Generally, the temperature program for a DSC analysis is designed such that the sample holder temperature increases linearly as a function of time.

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Online detection of baseline variations through torque measurements in isothermal reaction calorimeters

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