Recent progress in alkynylation with hypervalent iodine reagents

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The alkyne motif is a versatile functional group often encountered in organic chemistry. It can be involved in various transformations such as the alkyne-azide cycloaddition and has found widespread application in medicinal chemistry, chemical biology and ...

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Ethynylbenziodoxolones (EBXs) have recently emerged as potent reagents for the alkynylation of radicals. Their combination with photocatalysis allows the synthesis of valuable alkynes at room temperature. Herein, we discuss two photomediated strategies for ...

We report a copper-catalyzed alkynylation of azadipeptides using ethynylbenziodoxolone (EBX) reagents. Nonsymmetrical ynehydrazides could be obtained in 25–97% yield using azaglycine derivatives as nucleophiles. The transformation is compatible with most f ...

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Ethynylbenziodoxolones (EBXs) are commonly used as radical traps in photocatalytic alkynylations. Herein, we report that aryl-substituted EBX reagents can be directly activated by visible light irradiation. They act as both oxidants and radical traps, alle ...

Ethynylbenziodoxolones (EBXs) are commonly encountered reagents for the electrophilic alkynylation of nucleophiles. Herein, we report a one-pot, two-step process for EBX generation and their direct application in substrate functionalization. Our approach e ...

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Recent progress in alkynylation with hypervalent iodine reagents

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Novel Alkynylation Methods through the Combination of Hypervalent Iodine Reagents and Alkynyl-trifluoroborate Salts

New Applications of 1,3,2-Diazaphospholenes in Catalysis

Development of Hetero-Vinylbenziodoxolone Reagents for Applications in Synthetic Methodology and Biomolecule Functionalization

Synthesis of propargyl silanes from terminal alkynes via a migratory Sonogashira reaction

Synthesis and Applications of Ynimines and Enantioselective Total Synthesis of Artatrovirenol A

Hypervalent Iodine: New Reagents and Functionalization of Peptides

Radical Alkynylations with EthynylBenziodoXolones: From Photocatalysis to Direct Excitation

Copper-Catalyzed Alkynylation of Hydrazides: An Easy Access to Functionalized Azadipeptides

Exploring Photoredox-Catalyzed (Re)functionalizations with Core-Modified Benziodoxolones

Organic Chemistry and Synthesis Rely More and More upon Catalysts

Ring-Opening Reactions of Aminocyclopropanes and Aminocyclobutanes

Rh-catalyzed C-H Bond Heteroarylation with Hypervalent Iodine Reagents and Pd-Catalyzed Tethered Functionalizations of Carbon-Carbon Multiple Bonds

Photochemical Alkynylations with Hypervalent Iodine Reagents

Direct Photoexcitation of Ethynylbenziodoxolones: An Alternative to Photocatalysis for Alkynylation Reactions**

Tosyloxybenziodoxolone: A Platform for Performing the Umpolung of Alkynes in One-Pot Transformations

Copper‐Catalyzed Aza‐Sonogashira Cross‐Coupling to Ynimines: Development and Application to the Synthesis of Heterocycles

New Strategies for the Functionalization of Alkenes Exploiting Tethering Chemistry and Ring Strain

New Vinylation and Alkynylation Strategies with Hypervalent Iodine Reagents and Diazo Compounds

Copper-catalyzed transformations of carboradicals generated by electrochemical and photochemical methods: oxidative amination and polyfluoroarylation

Diamine Synthesis via the Nitrogen-Directed Azidation of sigma- and pi-C-C Bonds