Publication

Polyhydroxyazepanes mimicking monosaccharides: Synthesis of an alpha-D-galacto-like iminoheptitol

Pierre Vogel
2004
Journal Articles

Abstract

The synthesis of three new examples of seven-membered ring iminoalditols, displaying an extra hydroxymethyl group on the ring compared to the previously reported polyhydroxylated azepanes, has been achieved from D-lyxonolactone. None of them, including the alpha-D-galacto-like azepane (7), showed significant glycosidase inhibition on green coffee bean alpha-galactosidase and other commercially available hydrolases.

Official source

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Pierre Vogel
2004
Journal Articles

Abstract

Official source

Related concepts (7)

Chemical synthesis

In chemistry, chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as reagents or reactants) that will experience a transformation when subjected to certain conditions. Various reaction types can be applied to formulate a desired product.

Total synthesis

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