Linking a mutation to survival in wild mice

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Background: Reproductive isolation can result from adaptive processes (e.g., ecological speciation and mutation-order speciation) or stochastic processes such as "system drift" model. Ecological speciation predicts barriers to gene flow between populations ...

Realand imaginary -time quantum state evolutions are crucial in physics and chemistry for exploring quantum dynamics, preparing ground states, and computing thermodynamic observables. On near -term devices, variational quantum time evolution is a promising ...

Microbiome metabolism underlies numerous vital ecosystem functions. Individual microbiome members often perform partial catabolism of substrates or do not express all of the metabolic functions required for growth. Microbiome members can complement each ot ...

Aims. We derived galaxy colour selections from Euclid and ground-based photometry, aiming to accurately define background galaxy samples in cluster weak-lensing analyses. These selections have been implemented in the Euclid data analysis pipelines for gala ...

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Patterns in nature arise from processes interacting across a continuum of spatial scales, where new relationships emerge at each level of investigation. These patterns are nested features encompassing fine-scale local patterns, such as topography and geolo ...

We propose an adaptive quantum algorithm to prepare accurate variational time evolved wave functions. The method is based on the projected variational quantum dynamics (pVQD) algorithm, that performs a global optimization with linear scaling in the number ...

In high elevation Alpine areas, characterised by high snow accumulation and radiation-driven melt processes, the formation of peculiar ablation features called sun cups can be observed. Sun cups likely influence the energy and mass balance of the wet snowp ...

Roughness, defined as unevenness of material surfaces, plays an important role in determining how engineering components or natural objects interact with other bodies and their environment. The emergence of fractal roughness on natural and engineered surfa ...

The resilience of the mitochondrial genome (mtDNA) to a high mutational pressure depends, in part, on negative purifying selection in the germline. A paradigm in the field has been that such selection, at least in part, takes place in primordial germ cells ...

The past decades have seen the advent of information theory in various fields, from quantum physics to cosmology. At an intermediary scale between atomic and cosmological scales are biological systems and in particular the cell, as a constitutive element o ...

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

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Displaced communication, whereby individuals communicate regarding a subject that is not immediately present (spatially or temporally), is one of the key features of human language. It also occurs in a few animal species, most notably the honeybee, where t ...

Mutations to gene regulatory networks can be maladaptive or a source of evolutionary novelty. Epistasis con-founds our understanding of how mutations affect the expression patterns of gene regulatory networks, a chal-lenge exacerbated by the dependence of ...

The radial metallicity distribution of the Milky Way's disc is an important observational constraint for models of the formation and evolution of our Galaxy. It informs our understanding of the chemical enrichment of the Galactic disc and the dynamical pro ...

Streams draining proglacial floodplains harbor benthic biofilms comprised of diverse microbial communities. These high-mountain ecosystems are rapidly changing with climate warming, and it is therefore critical to better understand the mechanisms underlyin ...

We are used to defining network neutrality as absence of traffic differentiation, like policing or shaping. These mechanisms, however, are often not what determines end-users’ quality of experience (QoE). Most content today is accessed through edge caches, ...

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

Linking a mutation to survival in wild mice

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Reproductive isolation arises during laboratory adaptation to a novel hot environment

Variational quantum time evolution without the quantum geometric tensor

A framework for understanding collective microbiome metabolism

Euclid preparation XXXVII. Galaxy colour selections with Euclid and ground photometry for cluster weak-lensing analyses

Stability of a liquid layer draining around a horizontal cylinder: Interplay of capillary and gravity forces

At what spatial scale does natural selection operate? Using multiscale frameworks to calibrate the effects of environmental factors across landscape continuums

Adaptive projected variational quantum dynamics

Influence of sun cups on surface albedo of wet Alpine snowpack

How roughness emerges on natural and engineered surfaces

Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive

Information Theory in Transmembrane Transport

Impact of population size on early adaptation in rugged fitness landscapes

Individual and combined benefits of different nonequilibrium proofreading mechanisms

The evolution of behavioral cues and signaling in displaced communication

Environment-dependent epistasis increases phenotypic diversity in gene regulatory networks

The evolution of the Milky Way's thin disc radial metallicity gradient with K2 asteroseismic ages

Homogeneous Environmental Selection Structures the Bacterial Communities of Benthic Biofilms in Proglacial Floodplain Streams

Caching and Neutrality

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Identifying genetic and dietary modulators of metabolic disorders using systems genetics