Multi-cellular reconfigurable circuits : evolution, morphogenesis and learning

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The adaptation of organisms to their environment depends on the innovative potential inherent to genetic variation. In complex organisms such as mammals, processes like development and immunity require tight gene regulation. Complex forms emerge more often ...

Cells cope with and adapt to ever-changing environmental conditions. Sophisticated regulatory networks allow cells to adjust to these fluctuating environments. One such archetypal system is the Saccharomyces cerevisiae Pho regulon. When external inorganic ...

Harmful chemical compounds are released daily in warehouses, chemical plants and during environmental emergencies. Their uncontrolled dispersion contributes to the pollution of the atmosphere and threatens human and animal lives. When gas leaks occur, the ...

Modern machine learning (ML) models are capable of impressive performances. However, their prowess is not due only to the improvements in their architecture and training algorithms but also to a drastic increase in computational power used to train them.|S ...

A modular multiple frequency coils inductive link system to wirelessly provide power for at least a medical implant at an output of a receiving coil, whereby the receiving coil is configured to be implanted in an organism. The modular multiple frequency co ...

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

The design of an oil free turbocharger supported on herringbone grooved gas bearing was formulated as a multi-objective problem, which was solved by coupling a reduced order parametric model for gas bearing supported rotors with an evolutionary algorithm. ...

Cartilage homeostasis, crucial for musculoskeletal function, is orchestrated by interconnected biophysical cues. In healthy cartilage, repetitive compressive loading not only elicits a range of mechanical stimuli but also induces a gradual transient temper ...

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

In this thesis, we study two closely related directions: robustness and generalization in modern deep learning. Deep learning models based on empirical risk minimization are known to be often non-robust to small, worst-case perturbations known as adversari ...

Side-channel disassembly attacks recover CPU instructions from power or electromagnetic side-channel traces measured during code execution. These attacks typically rely on physical access, proximity to the victim device, and high sampling rate measuring in ...

Background: We previously described the KINSSHIP syndrome, an autosomal dominant disorder associated with intellectual disability (ID), mesomelic dysplasia and horseshoe kidney,caused by de novo variants in the degron of AFF3. Mouse knock-ins and overexpre ...

Edible robotics is an emerging research field with potential use in environmental, food, and medical scenarios. In this context, the design of edible control circuits could increase the behavioral complexity of edible robots and reduce their dependence on ...

Multi-cellular reconfigurable circuits : evolution, morphogenesis and learning

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Meeting our Makers: Uncovering the cis-regulatory activity of transposable elements using statistical learning

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Gas Sensing with Rotary-Wing Nano Aerial Vehicles

Byzantine-Resilient Learning Beyond Gradients: Distributing Evolutionary Search

A modular multiple frequency inductive link to wirelessly power multiple miniaturized implants

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Design and experimental investigation of a herringbone grooved gas bearing supported turbocharger

Synergetic Support of Cartilage Homeostasis via Coupled Thermal-Hydrostatic Pressure Stimuli

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Understanding generalization and robustness in modern deep learning

Instruction-Level Power Side-Channel Leakage Evaluation of Soft-Core CPUs on Shared FPGAs

Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles

Design and manufacture of edible microfluidic logic gates