Intake of Neutral Core Human Milk Oligosaccharides (hmos) During Early Life Improves Long-term Bone Quality

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While rapid progress has been made to characterize the bacterial and archaeal populations of the rumen microbiome, insight into how they interact with keystone protozoal species remains elusive. Here, we reveal two distinct system-wide rumen community type ...

Recent advancements in next-generation sequencing have revolutionized our understanding of the human microbiome. Despite this progress, challenges persist in comprehending the microbiome's influence on disease, hindered by technical complexities in species ...

Host–gut microbiota interactions are more complex than good or bad. Both gut symbiotic bacteria and pathobionts can provide essential functions to their host in one scenario and yet be detrimental to host health in another. So, these gut-dwelling bacteria ...

Background Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclei ...

Background The relationship between osteoporosis and intervertebral disc (IVD) degeneration remains controversial. Novel quantitative Dixon (Q-Dixon) and GRAPPATINI T2 mapping techniques have shown potential for evaluating the biochemical components of the ...

To comprehend the most detrimental characteristics behind bone fractures, it is key to understand the material and tissue level strain limits and their relation to failure sites. The aim of this study was to investigate the three-dimensional strain distrib ...

Patellar fracture and anterior knee pain remain major complications after Total Knee Arthroplasty (TKA). Patient-specific finite element (FE) models should help improve understanding of these complications through estimation of joint and bone mechanics. Ho ...

Objectives(i) To assess the effects of mechanical overloading on implant integration in rat tibiae, and (ii) to numerically predict peri-implant bone adaptation. Materials and methodsTranscutaneous titanium implants were simultaneously placed into both tib ...

Background. The impact of human genetic background on low-trauma fracture (LTF) risk has not been evaluated in the context of human immunodeficiency virus (HIV) and clinical LTF risk factors. Methods. In the general population, 6 common single-nucleotide p ...

Background: Disturbance to human microbiota may underlie several pathologies. Yet, we lack a comprehensive understanding of how lifestyle affects the dynamics of human-associated microbial communities. Results: Here, we link over 10,000 longitudinal measur ...

Purpose. To assess the effect of external mechanical microstimuli of controlled magnitude on the microarchitecture of the peri-implant bone beds in rat tibiae. Materials and Methods. Tibiae of forty rats were fitted with two transcutaneous titanium cylinde ...

A successful bone tissue engineering strategy entails producing bone-scaffold construct with adequate mechanical properties. Apart from the mechanical properties of the scaffold itself, the forming bone inside the scaffold also adds to the strength of the ...

In clinical situations, bone defects are often located at load bearing sites. Tissue engineering scaffolds are future bone substitutes and hence they will be subjected to mechanical stimulation. The goal of this study was to test if cyclic loading can be u ...

The fixation of an orthopedic implant depends strongly upon its initial stability. Peri-implant bone may resorb shortly after the surgery. This resorbtion is directly followed by new bone formation and implants fixation strengthening, the so-called seconda ...

A comparative characterization of the structure of normal and abnormal (osteoporotic) human lumbar and thoracic vertebrae samples was carried out to reveal the type of possible disorder. Samples from the bone fragments extracted during the surgery due to v ...

Intake of Neutral Core Human Milk Oligosaccharides (hmos) During Early Life Improves Long-term Bone Quality

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Protozoal populations drive system-wide variation in the rumen microbiome

Emergent ecological patterns and modelling of gut microbiomes in health and in disease

Pathobiont and symbiont contribute to microbiota homeostasis through Malpighian tubules–gut countercurrent flow in Bactrocera dorsalis

Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease

Q-Dixon and GRAPPATINI T2 Mapping Parameters: A Whole Spinal Assessment of the Relationship Between Osteoporosis and Intervertebral Disc Degeneration

Sub-trabecular strain evolution in human trabecular bone

Importance of trabecular anisotropy in finite element predictions of patellar strain after Total Knee Arthroplasty

Peri-implant bone adaptations to overloading in rat tibiae: experimental investigations and numerical predictions

Contribution of Genetic Background and Clinical Risk Factors to Low-Trauma Fractures in Human Immunodeficiency Virus (HIV)-Positive Persons: The Swiss HIV Cohort Study

Host lifestyle affects human microbiota on daily timescales

External Mechanical Microstimuli Modulate the Osseointegration of Titanium Implants in Rat Tibiae

In vivo loading increases mechanical properties of scaffold by affecting bone formation and bone resorption rates

In vivo cyclic loading as a potent stimulatory signal for bone formation inside tissue engineering scaffolds

Prediction of bone density around orthopedic implants delivering bisphosphonate

Scanning and transmission electron microscopy for evaluation of order/disorder in bone structure