Isolation and Characterisation of Regulators of the Septation Initiation Network Regulators in Fission Yeast

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Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) are one of the largest groups of transcription factors encoded by tetrapods, with 378 members in human alone. KZFP genes are often grouped in clusters reflecting amplification by ...

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Regulation of cytokinesis is essential for the cell during its division cycle. Failure to do so can lead to aneuploidy, which can be fatal and lead to senescence or cancer. A useful model organism for studying cytokinesis in eukaryotes is Schizosaccharomyc ...

H3K27M-mutant diffuse midline glioma (DMG) patients have no proven effective therapies. ONC201 has recently demonstrated efficacy in these patients, but the mechanism behind this remains unknown. We assessed clinical outcomes, tumor sequencing, and tissue/ ...

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Isolation and Characterisation of Regulators of the Septation Initiation Network Regulators in Fission Yeast

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Genetic features and genomic targets of human KRAB-zinc finger proteins

Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysis

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Engineered substrates incapable of induction of chondrogenic differentiation compared to the chondrocyte imprinted substrates

Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis

Self-supervised Dense Representation Learning for Live-Cell Microscopy with Time Arrow Prediction

Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures

Wide-scale identification of novel/eliminated genes responsible for evolutionary transformations

Characterisation of conditional alleles of the Schizosaccharomyces pombe cytokinesis regulator byr4

Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways

Microfluidic device combining hydrodynamic and dielectrophoretic trapping for the controlled contact between single micro-sized objects and application to adhesion assays

Deciphering the molecular events leading to the global restoration of the chromatin landscape during mitotic exit