Publications related to Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior

Related publications (15)

Mental State Recognition Deficits Linked to Brain Changes in Parkinson's Disease Without Dementia

Recent studies have reported social cognitive deficits, particularly in emotional processing, in Parkinson's disease (PD). However, a comprehensive characterization of these deficits and their underlying neural correlates remains elusive. Therefore, this s ...

2025

Fast High-Resolution Metabolite Mapping in the rat Brain Using 1H-FID-MRSI at 14.1 T

Cristina Ramona Cudalbu Moldovan, Bernard Lanz, Dunja Simicic, Jessie Julie Mosso, Thanh Phong Kevin Lê, Guillaume Miro André Briand, Brayan Alves

Magnetic resonance spectroscopic imaging (MRSI) enables the simultaneous noninvasive acquisition of MR spectra from multiple spatial locations inside the brain. Although 1H-MRSI is increasingly used in the human brain, it is not yet widely applied in the p ...

2025

Republication de : Evaluation of bone-conducted oVEMPs using frontal medial and mastoid stimulations

Maher Kayal

Aims: To determine the optimal stimulation intensity for frontal stimulation with a modified slit lamp holder and to compare the reliability and symmetry of bone-conducted ocular vestibular evoked myogenic potentials (oVEMPs) using two stimulation sites: f ...

2025

Long term effects of peripubertal stress on the thalamic reticular nucleus of female and male mice

Maria del Carmen Sandi Perez

Adverse experiences during infancy and adolescence have an important and enduring effect on the brain and are predisposing factors for mental disorders, particularly major depression. This impact is particularly notable in regions with protracted developme ...

Elsevier BV2024

Intelligent Neural Interfaces: An Emerging Era in Neurotechnology

Mahsa Shoaran, Uisub Shin, Mohammad Ali Shaeri

Integrating smart algorithms on neural devices presents significant opportunities for various brain disorders. In this paper, we review the latest advancements in the development of three categories of intelligent neural prostheses featuring embedded signa ...

2024 IEEE Custom Integrated Circuits Conference (CICC)2024

Personalized Clustering for Emotion Recognition Improvement

José Angel Miranda Calero

Emotion recognition through artificial intelligence and smart sensing of physical and physiological signals (affective computing) is achieving very interesting results in terms of accuracy, inference times, and user-independent models. In this sense, there ...

MDPI2024

Longitudinal functional brain connectivity maturation in premature newborn infants: Modulatory influence of early music enrichment

Dimitri Nestor Alice Van De Ville

Premature birth affects brain maturation, illustrated by altered brain functional connectivity at term equivalent age (TEA) and alters neurobehavioral outcome. To correct early developmental differences and improve neurological outcome, music during the ne ...

2024

Generalization and Personalization of Machine Learning for Multimodal Mobile Sensing in Everyday Life

Lakmal Buddika Meegahapola

A range of behavioral and contextual factors, including eating and drinking behavior, mood, social context, and other daily activities, can significantly impact an individual's quality of life and overall well-being. Therefore, inferring everyday life aspe ...

EPFL2024

Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysis

Maria del Carmen Sandi Perez

DNA methylation (DNAm) is one of the most frequently studied epigenetic mechanisms facilitating the interplay of genomic and environmental factors, which can contribute to externalizing behaviours and related psychiatric disorders. Previous epigenome-wide ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen

Adolescent individuals exhibit great variability in cortical dynamics and behavioral outcomes. The developing adolescent brain is highly sensitive to social experiences and environmental insults, influencing how personality traits emerge. A distinct patter ...

2023

Cyclo(His-Pro): A further step in the management of steatohepatitis

Johan Auwerx, Xiaoxu Li, Adrienne Joëlle Laurence Mottis, Alexis Rapin, Qi Wang, Alessia De Masi

Background & Aims: Non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) have become the world's most common liver diseases, placing a growing strain on healthcare systems worldwide. Nonetheless, no effective pharmacological treatment has be ...

ELSEVIER2023

Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis

Lijing Xin

Glutamatergic dysfunction is implicated in schizophrenia pathoaetiology, but this may vary in extent between patients. It is unclear whether inter-individual variability in glutamate is greater in schizophrenia than the general population. We conducted met ...

SPRINGERNATURE2023

Improved estimation of the risk of manic relapse by combining clinical and brain scan data

Erick Jorge Canales Rodriguez

Introduction: Estimating the risk of manic relapse could help the psychiatrist individually adjust the treatment to the risk. Some authors have attempted to estimate this risk from baseline clinical data. Still, no studies have assessed whether the estimat ...

2023

Increased Gray Matter Density in the Right Mesencephalic Tegmentum Is Associated with Better Engel Classes I and Ii After Radiosurgery for Hypothalamic Hamartomas

Constantin Tuleasca

BACKGROUND:Hypothalamic hamartomas (HHs) are disabling congenital lesions, responsible for gelastic seizures frequently associated with catastrophic epilepsies, epileptogenic encephalopathy, and cognitive and psychiatric severe comorbidities. Stereotactic ...

LIPPINCOTT WILLIAMS & WILKINS2022

Mapping of Structure-Function Age-Related Connectivity Changes on Cognition Using Multimodal MRI

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti

The relationship between age-related changes in brain structural connectivity (SC) and functional connectivity (FC) with cognition is not well understood. Furthermore, it is not clear whether cognition is represented via a similar spatial pattern of FC and ...

FRONTIERS MEDIA SA2022