Publications related to Disposable orbitally shaken TubeSpin bioreactor 600 for Sf9 cell cultivation in suspension

Related publications (48)

Primary data for EPFL thesis "Characterisation of conditional alleles of the Schizosaccharomyces pombe cytokinesis regulator byr4"

Regulation of cytokinesis is essential for the cell during its division cycle. Failure to do so can lead to aneuploidy, which can be fatal and lead to senescence or cancer. A useful model organism for studying cytokinesis in eukaryotes is Schizosaccharomyc ...

EPFL Infoscience2023

Characterisation of conditional alleles of the Schizosaccharomyces pombe cytokinesis regulator byr4

Michael Grüner Vindfeldt

Regulation of cytokinesis is essential for the cell during its division cycle. Failure to do so can lead to aneuploidy, which can be fatal and lead to senescence or cancer. A useful model organism for studying cytokinesis in eukaryotes is Schizosaccharomyc ...

EPFL2023

Intrinsically High Capacity of Animal Cells From a Symbiotic Cnidarian to Deal With Pro-Oxidative Conditions

Gaëlle Delphine Toullec

The cnidarian-dinoflagellate symbiosis is a mutualistic intracellular association based on the photosynthetic activity of the endosymbiont. This relationship involves significant constraints and requires co-evolution processes, such as an extensive capacit ...

FRONTIERS MEDIA SA2022

Deep MinCut: Learning Node Embeddings by Detecting Communities

Quoc Viet Hung Nguyen, Thành Tâm Nguyên, Chi Thang Duong

We present Deep MinCut (DMC), an unsupervised approach to learn node embeddings for graph -structured data. It derives node representations based on their membership in communities. As such, the embeddings directly provide insights into the graph structure ...

ELSEVIER SCI LTD2022

Engineering Agrobacterium tumefaciens Adhesion to Target Cells

Alix Kim Lan Pham, Alexandre Louis André Persat, Xavier Jean-Yves Pierrat, Zaïnebe Dhirani, Jeremy Pak Hei Wong

Agrobacterium tumefaciens is a plant pathogen commonly repurposed for genetic modification of crops. Despite its versatility, it remains inefficient at transferring DNA to many hosts, including to animal cells. Like many pathogens, physical contact between ...

AMER CHEMICAL SOC2022

Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

Pierre Gönczy, Georgios Hatzopoulos

Centrioles are eukaryotic organelles that template the formation of cilia and flagella, as well as organize the microtubule network and the mitotic spindle in animal cells. Centrioles have proximal-distal polarity and a 9 fold radial symmetry imparted by a ...

CELL PRESS2022

Direct measurement of the triple spin flip rate in dynamic nuclear polarization

Andrea Capozzi

A previous study of the effect of Gadolinium doping on the dynamic polarization (DNP) of C-13 using trityls showed that the rate at which the polarization builds up is almost independent of the Gadolinium concentration, while the electron spin-lattice rela ...

Academic Press Inc - Elsevier Science2021

Coupled segregation mechanisms of Sc, Zr and Mn at theta ' interfaces enhances the strength and thermal stability of Al-Cu alloys

Baptiste Thomas Jean Rouxel

The refinement and thermal stability of intermediate theta-prime (theta') precipitates are critical in the development of new high strength 2xxx series aluminium-copper (Al-Cu) alloys for high temperature applications. In this work, we use trace additions ...

PERGAMON-ELSEVIER SCIENCE LTD2021

High Sensitivity Detection of a Solubility Limiting Surface Transformation of Drug Particles by DNP SENS

David Lyndon Emsley, Arthur César Pinon, Jasmine Viger-Gravel

We investigate the presence of a surface species for the active pharmaceutical ingredient (API) AZD9496 with dynamic nuclear polarization surface enhanced nuclear spectroscopy (DNP SENS). We show that using DNP we can elucidate the presence of an amorphous ...

2021

Protrusion-retraction switches and traction forces in spontaneous cell polarization

Alicia Carine Bornert

Cell migration is a fundamental property of all animal cells which is involved in processes such as embryogenesis, immune response, tissue regeneration and cancer metastasis. Directional migration requires cell polarization which could happen in response t ...

EPFL2016

Coupling electrocoagulation and solar photocatalysis for electro- and photo-catalytic removal of carmoisine by Ag/graphitic carbon nitride: Optimization by process modeling and kinetic studies

Sami Rtimi

Graphitic carbon nitride, g-C3N4, have been receiving intense attention the last decades due to its unique physicochemical properties, and even more importantly, due to the visible light driven photoreactivity. Hence, the design and synthesis of novel phot ...

ELSEVIER2021

Chemical Genetic Screen Identifies Natural Products that Modulate Centriole Number

Zhou Fang, Michele Graciotti, Pierre Gönczy, Kai Johnsson

Centrioles are microtubule-based organelles found in most eukaryotic cells and that are critical for the formation of cilia and flagella, as well as of centrosomes in animal cells. The number of centrioles must be strictly regulated in proliferating cells ...

Wiley-Blackwell2016

Exergy and exergoeconomic analyses of sustainable furfural production via reactive distillation

François Maréchal

Lignocellulosic biomass is a potential renewable resource for production of high-value, sustainable products. Furfural is among the important bio-based chemicals in biorefineries. However, the conventional process of furfural production using a reaction-se ...

2021

Purification of centrosomes from mammalian cell lines

Paul Guichard

Centrosomes act as the main microtubule-organizing centre of animal cells and play critical roles in the cell, such as mitotic spindle organization, cell polarity, and motility. They are composed of two barrel-shaped structures, the centrioles, surrounded ...

Elsevier Academic Press Inc2015

Fluorogenic probes for live-cell imaging

Aleksandar Salim

The development of novel fluorogenic probes and their use in live-cell imaging lead to a plethora of discoveries in biological research. Herein I report on novel red fluorogenic probes for live-cell super-resolution microscopy of various cellular organelle ...

EPFL2020

The Engineering of a Scalable Disposable Orbitally Shaken Bioreactor System for Animal Cell Cultivation and Therapeutic Protein Production

Dominique Terry Monteil Jr

The aim of the pharmaceutical industry is to manufacture complex therapeutic proteins or biologics to treat human diseases. The manufacture of biologics requires a significant amount of financial and infrastructure resources. For this reason, efforts are b ...

EPFL2014

Uncertainty and sensitivity analysis of PWR mini-core transients in the presence of nuclear data uncertainty using non-parametric tolerance limits

Andreas Pautz, Alexander Aures

The impact of nuclear data uncertainties is studied for the reactor power and the reactivity during control rod withdrawal transients with reactivity insertions of 0.5

and 0.97

, respectively, for a PWR mini-core model. Multi-group cross sections, the mul ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Mechanisms of differential centriole inheritance in C. elegans

Lukas von Tobel

Centrosomes are the principal microtubule organizing center (MTOC) of animal cells and comprise a pair of centrioles surrounded by pericentriolar material (PCM). Centriole number must be carefully regulated to ensure bipolar spindle formation and thus fait ...

EPFL2014

Dissolved major and trace geochemical dynamics in Antarctic lacustrine systems

Tyler Joe Kohler

Clearwater Mesa Uames Ross Island, northeast Antarctic Peninsula) provides a unique opportunity to study solute dynamics and geochemical weathering in the pristine lacustrine systems of a high latitude environment. In order to determine major controls on t ...

Elsevier2020

Designing high ductility in magnesium alloys

William Curtin, Binglun Yin, Rasool Ahmad

The thermally activated pyramidal-to-basal (PB) transition of (c + a) dislocations, transforming glissile pyramidal dissociated core structures into sessile basal dissociated ones, lies at the origin of low ductility in pure magnesium (Mg). Solute-accelera ...

PERGAMON-ELSEVIER SCIENCE LTD2019