Publication

A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins

Rudolf Hovius, Luc Reymond
2022
Journal Articles

Abstract

We present a method probing the local membrane environment surrounding membrane proteins in the plasma membrane by linking a solvatochromic dye to the target, and provide evidence for lipid-based sorting. The insulin receptor environment changed upon insulin stimulation revealing dynamic local changes and distance dependence.

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A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins

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