Publications by Verena Rukes | EPFL Graph Search

Related publications (6)

A humoral stress response protects Drosophila tissues from antimicrobial peptides

Matteo Dal Peraro, Bruno Lemaitre, Chan Cao, Samuel Rommelaere, Jean Philippe Boquete, Verena Rukes, Fernando Augusto Teixeira Pinto Meireles, Alexia Laurie Carboni

An efficient immune system must provide protection against a broad range of pathogens without causing excessive collateral tissue damage. While immune effectors have been well characterized, we know less about the resilience mechanisms protecting the host ...

Elsevier BV2024

Nanopore Technology: When Proteins Analyse Proteins

Verena Rukes

Nanopore sensing is an emerging technology that can distinguish subtle differences in molecules and allows the observation of molecular processes. The technique has revolutionized DNA sequencing through long reads of single molecules. Following this succes ...

Swiss Chemical Society2025

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore

Hilal Lashuel, Matteo Dal Peraro, Anass Chiki, Chan Cao, Lucien Fabrice Krapp, Pedro José Santana Ribeiro Magalhães, Juan Francisco Bada Juarez, Verena Rukes, Simon Finn Mayer

Protein post-translational modifications (PTMs) play a crucial role in countless biological processes, profoundly modulating protein properties on both spatial and temporal scales. Protein PTMs have also emerged as reliable biomarkers for several diseases. ...

Amer Chemical Soc2023

Advancing nanopore technology toward protein identification and sequencing

Verena Rukes

Proteins drive most cellular functions and are key players in diseases, yet proteomics still lags behind genomics due to the complexity, diversity, and dynamic nature of proteoforms. Nanopore technology – known for real-time, single-molecule DNA sequencing ...

2025

Single-molecule evidence of Entropic Pulling by Hsp70 chaperones

Paolo De Los Rios, Chan Cao, Verena Rukes, Mathieu Rebeaud

Hsp70 chaperones are central components of the cellular network that ensures the structural quality of proteins. Despite crucial roles in processes such as protein disaggregation and protein translocation into organelles, their physical mechanism of action ...

Nature Research2024

Eliminating the Interference of Neighboring Nucleobases in Aerolysin for Nanopore Sequencing

Verena Rukes

Biological nanopores have revolutionized DNA sequencing with their incredible advantages of long reads, high throughput, portability, and low material requirement. Despite numerous improvements, base calling remains challenging due to the influence of neig ...

AMER CHEMICAL SOC2025