Publications by Cristina Colangelo

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Neuromodulators, such as acetylcholine (ACh), control information processing in neural microcircuits by regulating neuronal and synaptic physiology. Computational models and simulations enable predictions on the potential role of ACh in reconfiguring netwo ...

Neuromodulation of neocortical microcircuits is one of the most fascinating and mysterious aspects of brain physiology. Despite over a century of research, the neuroscientific community has yet to uncover the fundamental biological organizing principles un ...

The CA1 region of the hippocampus is one of the most studied regions of the rodent brain, thought to play an important role in cognitive functions such as memory and spatial navigation. Despite a wealth of experimental data on its structure and function, i ...

The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction in the neocortex by releasing acetylcholine (ACh). ACh release dynamically rec ...

Cristina Colangelo

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Data-Driven Modeling of Cholinergic Modulation of Neural Microcircuits: Bridging Neurons, Synapses and Network Activity

Neuromodulation of neocortical microcircuitry: a multi-scale framework to model the effects of cholinergic release

Community-based reconstruction and simulation of a full-scale model of region CA1 of rat hippocampus

Cellular, Synaptic and Network Effects of Acetylcholine in the Neocortex

Distinct Activity Profiles of Somatostatin-Expressing Interneurons in the Neocortex