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Friedhelm Christoph Hummel

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Related publications (88)

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EPFL-Smart-Kitchen-30 Annotations and Poses

Silvestro Micera, Friedhelm Christoph Hummel, Solaiman Shokur, Alexander Mathis, Mahdi Hamidi Rad, Haozhe Qi, Franklin Leong, Andy Bonnetto, Matea Tashkovska

Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex actions are naturally exhibited in kitchens from choppi ...

Zenodo2025

The structural connectome and motor recovery after stroke: predicting natural recovery

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Gabriel Girard, Takuya Morishita, Maximilian Jonas Wessel, Chang-Hyun Park, Elena Beanato, Philip Egger, Philipp Johannes Koch, Giorgia Giulia Evangelista

Stroke patients vary considerably in terms of outcomes: some patients present ‘natural’ recovery proportional to their initial impairment (fitters), while others do not (non-fitters). Thus, a key challenge in stroke rehabilitation is to identify individual ...

2021

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Elena Beanato, Traian Popa, Pierre Theopistos Vassiliadis, Fabienne Windel, Esra Neufeld

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Nature Portfolio2024

A Novel Patient-Tailored, Cumulative Neurotechnology-Based Therapy for Upper-Limb Rehabilitation in Severely Impaired Chronic Stroke Patients: The AVANCER Study Protocol

Christina Henneken, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Elena Beanato, Andrea Crema, Giorgia Giulia Evangelista, Claudia Bigoni, Sarah Bernardina Zandvliet, Julie Loréline Valériane Hervé, Meltem Oflar

Effective, patient-tailored rehabilitation to restore upper-limb motor function in severely impaired stroke patients is still missing. If suitably combined and administered in a personalized fashion, neurotechnologies offer a large potential to assist reha ...

FRONTIERS MEDIA SA2022

Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities

Friedhelm Christoph Hummel, Estelle Emeline Raffin

More than 1.5 million people suffer a stroke in Europe per year and more than 70% of stroke survivors experience limited functional recovery of their upper limb, resulting in diminished quality of life. Therefore, interventions to address upper-limb impair ...

2018

The functional role of beta‐oscillations in the supplementary motor area during reaching and grasping after stroke: A question of structural damage to the corticospinal tract

Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Hand motor function is often severely affected in stroke patients. Non-satisfying recovery limits reintegration into normal daily life. Understanding stroke-related network changes and identifying common principles that might underlie recovered motor funct ...

Wiley2019

Native learning ability and not age determines the effects of brain stimulation

Friedhelm Christoph Hummel, Traian Popa, Pablo Maceira Elvira, Andéol Geoffroy Cadic-Melchior, Anne-Christine Schmid

Healthy aging often entails a decline in cognitive and motor functions, affecting independence and quality of life in older adults. Brain stimulation shows potential to enhance these functions, but studies show variable effects. Previous studies have tried ...

2024

Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Laurijn Rianne Draaisma

Stroke is a main cause for long-term disability. Stroke symptoms cover various domains, e.g., motor, sensory, language, or other cognitive functions. In clinical practice and rehabilitation research, especially motor impairment attracts much attention. How ...

2020

Novel personalized treatment strategy for patients with chronic stroke with severe upper-extremity impairment: The first patient of the AVANCER trial

Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Elena Beanato, Sylvain Jean-François Harquel, Andrea Crema, Giorgia Giulia Evangelista, Claudia Bigoni, Sarah Bernardina Zandvliet, Julie Loréline Valériane Hervé, Meltem Oflar

Background: Around 25% of patients who have had a stroke suffer from severe upper-limb impairment and lack effective rehabilitation strategies. The AVANCER proof-of-concept clinical trial (NCT04448483) tackles this issue through an intensive and personaliz ...

CELL PRESS2023

Impact of spindle-inspired transcranial alternating current stimulation during a nap on sleep-dependent motor memory consolidation in healthy older adults

Chan Sol Park, Friedhelm Christoph Hummel, Takuya Morishita, Manon Chloé Durand-Ruel, Roberto Felipe Salamanca Giron, Maeva Moyne

With the increase in life expectancy and the rapid evolution of daily life technologies, older adults must constantly learn new skills to adapt to society. Sleep reinforces skills acquired during the day and is associated with the occurrence of specific os ...

Oxford University Press (OUP)2025

Effect of Extrinsic Reward on Motor Plasticity during Skill Learning

Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis

Human motor skill acquisition is improved by performance feedback, and coupling such feedback with extrinsic reward (such as money) can enhance skill learning. However, the neurophysiology underlying such behavioral effect is unclear. To bridge this gap, w ...

2025

Early motor skill acquisition in healthy older adults: brain correlates of the learning process

Friedhelm Christoph Hummel, Takuya Morishita, Chang-Hyun Park, Pablo Maceira Elvira, Manon Chloé Durand-Ruel, Maeva Moyne

Motor skill learning is a crucial process at all ages. However, healthy aging is often accompanied by a reduction in motor learning capabilities. This study characterized the brain dynamics of healthy older adults during motor skill acquisition and identif ...

OXFORD UNIV PRESS INC2023

Brain connectome correlates of short-term motor learning in healthy older subjects

Friedhelm Christoph Hummel, Takuya Morishita, Chang-Hyun Park, Manon Chloé Durand-Ruel, Maeva Moyne

The motor learning process entails plastic changes in the brain, especially in brain network reconfigurations. In the current study, we sought to characterize motor learning by determining changes in the coupling behaviour between the brain functional and ...

Elsevier Masson, Corp Off2023

Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke

Silvestro Micera, José del Rocio Millán Ruiz, Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Martina Coscia

Upper limb motor deficits in severe stroke survivors often remain unresolved over extended time periods. Novel neurotechnologies have the potential to significantly support upper limb motor restoration in severely impaired stroke individuals. Here, we revi ...

2019

Improved Spinal Cord FMRI Activation Mapping Using Regularized Hemodynamic Deconvolution

Takuya Ishii, Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Ekansh Sareen

The spinal cord plays a central role in regulating sensorimotor functions through complex neural pathways. However, detailed investigation of these mechanisms remains a developing field. In this study, we propose a multimodal approach combining transcrania ...

IEEE2025

Congruency effects can compensate for deficits of healthy older adults in crossmodal integration

Friedhelm Christoph Hummel

One of the pivotal challenges of aging is to maintain independence in the activities of daily life. In order to adapt to changes in the environment, it is crucial to continuously process and accurately combine simultaneous input from different sensory syst ...

2019

Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Elena Beanato, Pierre Theopistos Vassiliadis, Fabienne Windel

Objective. Selective neuromodulation of deep brain regions has for a long time only been possible through invasive approaches, because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques. Approach. An appr ...

Iop Publishing Ltd2024

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)

Friedhelm Christoph Hummel, Simone Rossi

A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations t ...

ELSEVIER IRELAND LTD2020

An automatized method to determine latencies of motor-evoked potentials under physiological and pathophysiological conditions

Friedhelm Christoph Hummel, Takuya Morishita, Pierre Theopistos Vassiliadis, Andéol Geoffroy Cadic-Melchior, Claudia Bigoni

Background. Latencies of motor evoked potentials (MEPs) can provide insights into the motor neuronal pathways activated by transcranial magnetic stimulation. Notwithstanding its clinical relevance, accurate, unbiased methods to automatize latency detection ...

IOP Publishing Ltd2022

Brain networks and their relevance for stroke rehabilitation

Friedhelm Christoph Hummel, Philipp Johannes Koch

Stroke has long been regarded as focal disease with circumscribed damage leading to neurological deficits. However, advances in methods for assessing the human brain and in statistics have enabled new tools for the examination of the consequences of stroke ...

2019