Marion Marie-Agnès Garreau

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If small molecules have led to tremendous progress in curing diseases, new therapeutic agents such as peptides or antibody-drugs conjugates have emerged as a highly promising next generation of pharmaceuticals. As for small molecules, their derivatization ...

We report the first decarboxylative alkynylation of the C-terminus of peptides starting from free carboxylic acids. The reaction is fast, metal-free, and proceeds cleanly to afford alkynylated peptides with a broad tolerance for the C-terminal amino acid. ...

The development of novel methodologies for the functionalization of saturated heterocycles is highly desirable. Herein, we report a cheap and efficient photochemical method for the C-H functionalization of saturated O-heterocycles, as well as the deconstru ...

An organic photoredox catalyst, 4CzIPN, was used in combination with a copper catalyst, CuCl, to effect decarboxylative C(sp3)–N coupling. The coupling worked with both anilines and imines as nitrogen sources and could be used to prepare a variety of alkyl ...

Organic dyes have emerged as a reliable class of photoredox catalysts. Their great structural variety combined with the easy finetuning of their electronic properties has unlocked new possibilities for the generation of reactive intermediates. In this revi ...

In this issue of Chem, Powers and co-workers demonstrate that iodanyl radicals are the key oxidants and chain carriers in a proposed open-shell mechanism for the aerobic synthesis of hypervalent iodine compounds. ...

A photoredox-catalyzed oxidative decarboxylative coupling of small peptides is reported, giving access to a variety of N,O-acetals. They were used as intermediates for the addition of phenols and indoles, leading to novel peptide scaffolds and bioconjugate ...

Marion Marie-Agnès Garreau

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Development of Photocatalysts towards the Visible-Light driven C-Terminal Bioconjugation of Peptides and Proteins

C-Terminal Bioconjugation of Peptides through Photoredox Catalyzed Decarboxylative Alkynylation

Photochemical Functionalization of Heterocycles with EBX Reagents: C-H Alkynylation versus Deconstructive Ring Cleavage

Tandem Photoredox and Copper-Catalyzed Decarboxylative C(sp3)–N Coupling of Anilines and Imines Using an Organic Photocatalyst

Photocatalysis with organic dyes: facile access to reactive intermediates for synthesis

An Alternative One-Electron Oxidation Strategy to Access Hypervalent Iodine Reagents

Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification